Windtree Therapeutics Stock (NASDAQ: WINT)

Dernières nouvelles pour Windtree Therapeutics (NASDAQ:WINT) Stock

Windtree Therapeutics

Windtree Therapeutics Inc is a biotechnology company focused on advancing early and late-stage innovative therapies for critical conditions and diseases. Its portfolio of product candidates includes istaroxime, a Phase 2 candidate with sarco endoplasmic reticulum Ca2+ -ATPase 2a, or SERCA2a, activating properties for acute heart failure and associated cardiogenic shock, preclinical SERCA2a activators for heart failure, rostafuroxin for the treatment of hypertension in patients with a specific genetic profile, and a preclinical atypical protein kinase C iota, or aPKCi, inhibitor, being developed for potential application in rare and broad oncology indications. It operates in one operating segment, which is the research and development of products focused on cardiovascular disease.

Windtree Therapeutics, Inc. - Common Stock

Windtree Therapeutics Inc

Windtree Therapeutics Inc arrants (25/03/2026)

WINTO GROUP HLDGS LTD by WINTO GROUP HLDGS LTD.

Wintrust Financial Corporation - Common Stock

Wintrust Financial Corp

Wintrust Financial Corporation - Fixed-to-Floating Rate Non-Cumulative Perpetual Preferred Stock, Series D

Wintrust Financial Corporation - Depositary Shares, Each Representing a 1/1,000th Interest in a Share of 6.875% Fixed-Rate Reset Non-Cumulative Perpetual Preferred Stock, Series E

Lamb Weston Holdings, Inc. (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/LW#NYSE">LW</a>) will release its third-quarter earnings results before the <a href="https://www.benzinga.com/quote/LW/earnings">opening bell on Thursday, April 3.</a>
Analysts expect the Eagle, Idaho-based company to report quarterly earnings at 87 cents per share, down from $1.2 per share in the year-ago period. According to data from <a href="https://pro.benzinga.com/dashboard">Benzinga Pro</a>, Lamb Weston projects quarterly revenue at $1.49 billion, compared to $1.46 billion a year earlier.
On March 20, Lamb Weston declared a quarterly dividend of 37 cents per share.
Lamb Weston shares gained 1.6% to close at $54.15 on Wednesday.
Benzinga readers can access the latest analyst ratings on the <a href="https://www.benzinga.com/analyst-ratings/analyst-color/22/09/28888638/exclusive-study-finds-benzinga-analyst-ratings-data-yields-market-beating-strategie">Analyst Stock Ratings</a> page. Readers can sort by stock ticker, company name, analyst firm, rating change or other variables.
Let's have a look at how Benzinga's most-accurate <a href="https://www.benzinga.com/quote/GBX/analyst-ratings">analysts have rated the company</a> in the recent period.
<ul>
<li>Barclays analyst Lauren Lieberman maintained an Overweight rating and cut the price target from $87 to $60 on Dec. 23, 2024. This analyst has an accuracy rate of 62%.</li>
<li>Stifel analyst Matthew Smith maintained a Hold rating and cut the price target from $80 to $68 on Dec. 20, 2024. This analyst has an accuracy rate of 62%.</li>
<li>Jefferies analyst Rob Dickerson maintained a Buy rating and raised the price target from $80 to $95 on Dec. 17, 2024. This analyst has an accuracy rate of 68%.</li>
<li>JP Morgan analyst Ken Goldman maintained a Neutral rating and boosted the price target from $68 to $78 on Dec. 16, 2024. This analyst has an accuracy rate of 78%.</li>
<li>Deutsche Bank analyst Steve Powers initiated coverage on the stock with a Hold rating and a price target of $81 on Dec. 12, 2024. This analyst has an accuracy rate of 71%.</li>
</ul>
Considering buying LW stock? Here&#8217;s what analysts think: 
<figure class="wp-block-image size-large is-resized"><img loading="lazy" decoding="async" width="1024" height="574" src="https://editorial-assets.benzinga.com/wp-content/uploads/2025/04/03031420/image-1-5-1024x574.png" alt="" class="wp-image-854653" style="width:583px;height:auto" srcset="https://editorial-assets.benzinga.com/wp-content/uploads/2025/04/03031420/image-1-5-1024x574.png 1024w,https://editorial-assets.benzinga.com/wp-content/uploads/2025/04/03031420/image-1-5-300x168.png 300w,https://editorial-assets.benzinga.com/wp-content/uploads/2025/04/03031420/image-1-5-768x430.png 768w,https://editorial-assets.benzinga.com/wp-content/uploads/2025/04/03031420/image-1-5.png 1117w" sizes="(max-width: 1024px) 100vw, 1024px" /></figure>
Read This Next: 
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<li><a href="https://www.benzinga.com/25/04/44604078/wall-streets-most-accurate-analysts-give-their-take-on-3-defensive-stocks-with-over-6-dividend-yields">Wall Street&#8217;s Most Accurate Analysts Give Their Take On 3 Defensive Stocks With Over 6% Dividend Yields</a> </li>
</ul>
Photo via Shutterstock

Earnings

News

Price Target

Pre-Market Outlook

Markets

Analyst Ratings

Trading Ideas

Top Wall Street Forecasters Revamp Lamb Weston Price Expectations Ahead Of Q3 Earnings

Legendary stock picker Warren Buffett has refused to include cryptocurrencies, including Bitcoin (CRYPTO: <a class="ticker" href="https://www.benzinga.com/quote/btc/usd">BTC</a>), in his firm Berkshire Hathaway Inc.'s (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/BRK#NYSE">BRK</a>) (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/BRK#NYSE">BRK</a>) portfolio, but the holding company, interestingly, has exposure to a firm that pitches the apex cryptocurrency as an inflation hedge.
What happened: According to the latest 13F filing, Berkshire Hathaway holds 433,558 shares of financial services company Jefferies Financial Group Inc. (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/JEF#NYSE">JEF</a>), worth nearly $34 million.
The New York City-headquartered firm operates in investment banking and capital markets, and asset management businesses.
Notably, Jefferies holds a sizeable stake in iShares Bitcoin Trust ETF (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/IBIT#NASDAQ">IBIT</a>), the world's largest spot exchange-traded Bitcoin fund. Filings with the SEC revealed that Jefferies owned 1,615,731 shares of IBIT, valued at over $85 million.
See Also:<a href="https://www.benzinga.com/24/12/42735744/pharma-bro-martin-shkreli-predicts-doom-for-michael-saylors-microstrategy-as-stock-dips-below-300-in-after-hours-trading"> </a><a href="https://www.benzinga.com/25/04/44621245/gold-backed-cryptos-match-yellow-metals-highs-following-trumps-liberation-day-shock">Bitcoin Reeling From Trump&#8217;s &#8216;Liberation Day&#8217; Shock But These Gold-Backed Coins Are Killing It This Year</a>
The investment likely stemmed from its bullish long-term view about the leading digital asset.
Jefferies deemed Bitcoin as a "critical hedge" against fiat debasement and inflation, <a href="https://www.cnbc.com/2023/10/05/bitcoin-is-a-critical-hedge-against-currency-debasement-and-return-of-inflation-jefferies-says.html">according </a>to an October 2023 report by CNBC.
The investment bank said Bitcoin's insurance policy narrative gained traction following the <a href="https://www.benzinga.com/news/23/06/32705921/us-banking-crisis-spurs-756-billion-capital-surge-into-cash-funds-says-bank-of-america">U.S. banking crisis</a> earlier in the year, and it recommended a 10% allocation to the asset for U.S. dollar-based long-term global investors.
This optimism sharply contrasted with Buffett&#8217;s dismissive attitude toward Bitcoin. The &#8220;Oracle of Omaha&#8221; called Bitcoin &#8220;probably rat poison squared&#8221; during Berkshire Hathaway&#8217;s annual&nbsp;<a href="https://www.benzinga.com/general/24/03/37513063/warren-buffett-says-he-wouldnt-pay-25-for-all-the-bitcoin-in-the-world-he-considers-crypto-rat-poiso" target="_blank" rel="noreferrer noopener">shareholder</a>&nbsp;meeting in 2018 and predicted a &#8220;bad ending&#8221; for the cryptocurrency.
Price Action:&nbsp; At the time of writing, Bitcoin was exchanging hands at $83,315.66, down 1.03% in the last 24 hours, according to <a href="https://pro.benzinga.com/dashboard?_gl=1&#x2A;380nj0&#x2A;_ga&#x2A;MTEyOTAyOTcxMy4xNzEzMzY0NTYy&#x2A;_ga_V7ZK73W7N0&#x2A;MTcxNDk4MzIzMi42LjEuMTcxNDk4OTE0Ni4wLjAuMA..">data from Benzinga Pro</a>. Year-to-date, the asset has slid 11.84%.
Shares of Berkshire Hathaway fell 2.09% in after-hours trading, after closing 0.89% higher at 537.72 during Wednesday&#8217;s regular session. Jefferies stock closed 2.99% higher at $55.14.
Berkshire Hathaway stock demonstrated a good momentum and value score as of this writing. To see how Jefferies and other financial stocks rank in these categories, <a href="https://www.benzinga.com/premium/ideas/benzinga-edge-2#:~:text=Turn%20Market%20Chaos,when%20markets%20rebound">visit </a>Benzinga Edge Stock Rankings.
<figure class="wp-block-image size-full"><img loading="lazy" decoding="async" width="441" height="172" src="https://editorial-assets.benzinga.com/wp-content/uploads/2025/04/03022349/Screenshot-2025-04-03-114944.png" alt="" class="wp-image-854549" srcset="https://editorial-assets.benzinga.com/wp-content/uploads/2025/04/03022349/Screenshot-2025-04-03-114944.png 441w,https://editorial-assets.benzinga.com/wp-content/uploads/2025/04/03022349/Screenshot-2025-04-03-114944-300x117.png 300w" sizes="(max-width: 441px) 100vw, 441px" /></figure>
Image via Shutterstock
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Coverage of Bitcoin, Etherum, Ripple and all the latest digital currencies.

Cryptocurrency

$BTC

IBIT

Warren Buffett Avoids Bitcoin, But Do You Know Berkshire Hathaway Owns Stake In A Company That Pitches BTC As 'Critical' Inflation Hedge

Vinod Khosla, an early investor in OpenAI and the founder of Khosla Ventures, shared his views on what startup founders should expect from investors, criticizing the &#8220;founder-friendly&#8221; culture in the Silicon Valley.
What Happened: In a conversation on the Minus One podcast posted on Wednesday, Khosla said that while the term &#8220;founder-friendly&#8221; is often used in venture capital circles, it doesn't truly benefit entrepreneurs in the long run.
"I hate the culture — there&#8217;s a number of firms in the valley who push the idea we are founder friendly," he stated in response to a question about what founders should look for in investors. "What [it] really means, they're never going to challenge you. They want to be popular with you as opposed to help you."
See Also: <a href="https://www.benzinga.com/personal-finance/24/10/41196355/ai-will-do-most-jobs-better-faster-cheaper-silicon-valley-billionaire-vinod-khosla-calls-for-uni">AI Will Do Most Jobs &#8216;Better, Faster, Cheaper&#8217;: Silicon Valley Billionaire Vinod Khosla Calls For Universal Basic Income</a>
Khosla, who has been investing in startups for over 40 years, described his role as a &#8220;venture assistant,&#8221; not a traditional venture capitalist. He argued that successful investors don't just write checks but provide invaluable guidance, especially when a startup is incomplete in certain aspects.&nbsp;
"Great founders, the majority of the time, are incomplete in some dimension," he stated, adding, "Your job as an investor is to help them with that."
He also touched on the importance of &#8220;brutally honest&#8221; feedback, saying that 95% of the feedback founders get from investors is often &#8220;hypocritical politeness&#8221; that feels good but doesn't help their growth.&nbsp;
Founders should strive for a real, well-intended critique of their strategy, something that challenges them to think, he said.&nbsp;
Subscribe to the&nbsp;<a href="https://bztechtrends.beehiiv.com/subscribe" target="_blank" rel="noreferrer noopener">Benzinga Tech Trends newsletter</a>&nbsp;to get all the latest tech developments delivered to your inbox.
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<iframe loading="lazy" title="Why I Backed OpenAI, AGI, &amp; the Zero to One Team &#x7C; Vinod Khosla" width="500" height="281" src="https://www.youtube.com/embed/shMMW_RhztA?feature=oembed" frameborder="0" allow="accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share" referrerpolicy="strict-origin-when-cross-origin" allowfullscreen></iframe>
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Why It Matters: As the founder of Khosla Ventures, Khosla has been instrumental in backing experimental technologies such as biomedicine, robotics, and AI. Notably, he was one of the early investors in OpenAI and <a href="https://www.benzinga.com/news/23/12/36056265/openai-investor-vinod-khosla-works-80-hours-a-week-will-use-peter-thiels-anti-aging-methods-if-they">invested $50 million</a> in the parent company of ChatGPT.
Khosla is also known <a href="https://www.benzinga.com/news/23/12/36056265/openai-investor-vinod-khosla-works-80-hours-a-week-will-use-peter-thiels-anti-aging-methods-if-they">for his involvement</a> in Sun Microsystems, which he co-founded in 1982. The company was later acquired by Oracle. Khosla's work at Kleiner Perkins, before founding his own venture fund, further cemented his reputation as a visionary investor in technology.
With a reported net worth of $7.7 billion, <a href="https://www.forbes.com/profile/vinod-khosla/">according</a> to Forbes, Khosla has built a career based on taking calculated risks in areas that other investors often overlook. His firm, Khosla Ventures, has backed major successes like Affirm and DoorDash.
Photo Courtesy: ahmad.faizal On Shutterstock.com
Check out more of Benzinga&#8217;s Consumer Tech coverage by&nbsp;<a href="https://www.benzinga.com/topic/consumer-tech" target="_blank" rel="noreferrer noopener">following this link</a>.
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</ul>
Disclaimer: This content was partially produced with the help of&nbsp;<a href="https://www.benzinga.com/author/benzinga-neuro" target="_blank" rel="noreferrer noopener">Benzinga Neuro</a>&nbsp;and was reviewed and published by Benzinga editors.

Tech

Vinod Khosla Was An Early Investor In OpenAI But He's No Fan Of Founder-Friendly Venture Capitalism: 'I Hate The Culture'

VSAT

Riyadh Air Taps Viasat For Industry-Leading Onboard Streaming And Wi-Fi, Elevating Premium Guest Experience

President Donald Trump has reportedly imposed reciprocal tariffs on some of the world&#8217;s most remote and uninhabited locations, along with various global trade partners, on &#8216;Liberation Day.&#8217;
What Happened: The Trump administration declared a 10% reciprocal tariff on the Heard and McDonald Islands, an uninhabited Australian external territory situated approximately 1,000 miles north of Antarctica, <a href="https://www.forbes.com/sites/antoniopequenoiv/2025/04/02/trump-imposes-tariffs-on-uninhabited-heard-and-mcdonald-islands-remotest-places-on-earth/">reported</a> Forbes.  The Australian government website describes these islands as &#8220;one of the wildest and remotest places on Earth&#8221;.
These tariffs also apply to other regions, including the British Indian Ocean Territory, the Cocos (Keeling) Islands, which have fewer than 600 residents, Norfolk Island, and the Norwegian Arctic islands of Svalbard and Jan Mayen, which have no permanent population.
The impact of these tariffs&nbsp;on the Heard and McDonald&nbsp;Islands remains uncertain due to their minimal economic activity, which is limited to some Australian commercial fishing in their economic zone.
See Also: <a href="https://benzinga.com/markets/equities/25/04/44620650/nvidia-amd-apple-meta-tesla-why-these-5-stocks-are-trending-on-trumps-liberation-day" target="_blank" rel="noreferrer noopener">Nvidia, AMD, Apple, Meta, Tesla: Why These 5 Stocks Are Trending On Trump&#8217;s Liberation Day </a>
Why It Matters: The imposition of tariffs on such remote and uninhabited locations raises questions about the rationale behind these decisions. For instance, Norfolk Island exported goods worth $655,000 to the U.S. in 2023, the main export being leather footwear worth $413,000, <a href="https://oec.world/en/profile/country/nfk">according </a>to Observatory of Economic Complexity data. However, the administrator of Norfolk Island, George Plant, refuted these figures and told The Guardian that there are no known exports from Norfolk Island to the U.S.
Similarly, the Heard Island and McDonald Islands, which are Australia&#8217;s &#8216;external territories&#8217;, reportedly exported products worth $1.4 million to the U.S. in 2022, primarily &#8220;machinery and electrical&#8221; imports, according to World Bank data. The nature of these goods remains unclear. In the previous five years, imports from these islands ranged from $15,000 to $325,000 per year.
The Australian prime minister, Anthony Albanese, told the publication, "Nowhere on earth is safe."<a href="https://www.theguardian.com/us-news/2025/apr/02/trump-new-tariffs-liberation-day"></a>
China has been <a href="https://www.benzinga.com/news/global/25/04/44620889/trumps-liberation-day-tariffs-roil-markets-as-china-slams-typical-unilateral-bullying-asian-markets-plunge">most affected</a> by Trump&#8217;s &#8216;Liberation Day&#8217; tariffs, with a 34% tax on top of the existing 20% tariffs on Chinese imports. Meanwhile,&nbsp;Canada and Mexico have been&nbsp;exempted from the baseline 10% tariff rate as the U.S. considers imposing&nbsp;a 25% tariff on the majority of imports from these countries. 
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</ul>
Image via Shutterstock
Disclaimer:&nbsp;This content was partially produced with the help of AI tools and was reviewed and published by Benzinga editors.

Trump Imposes Tariffs On Uninhabited Islands And Remote Locations: World Bank Data Raises Questions

Conagra Brands, Inc. (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/CAG#NYSE">CAG</a>) will release its third-quarter earnings results before the <a href="https://www.benzinga.com/quote/CAG/earnings">opening bell on Thursday, April 3</a>.
Analysts expect the Chicago-based company to report quarterly earnings at 53 cents per share, down from 69 cents per share in the year-ago period. According to data from <a href="https://pro.benzinga.com/dashboard">Benzinga Pro</a>, Conagra projects quarterly revenue at $2.9 billion, compared to $3.03 billion a year earlier.
Conagra Brands announced on Tuesday that it's teaming up with Bloom Energy Corp (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/BE#NYSE">BE</a>) to integrate advanced fuel cell technology at two of its Ohio manufacturing plants.
Conagra Brands shares fell 0.8% to close at $26.38 on Wednesday.
Benzinga readers can access the latest analyst ratings on the <a href="https://www.benzinga.com/analyst-ratings/analyst-color/22/09/28888638/exclusive-study-finds-benzinga-analyst-ratings-data-yields-market-beating-strategie">Analyst Stock Ratings</a> page. Readers can sort by stock ticker, company name, analyst firm, rating change or other variables.
Let's have a look at how Benzinga's most-accurate <a href="https://www.benzinga.com/quote/CAG/analyst-ratings">analysts have rated the company</a> in the recent period.
<ul>
<li>Morgan Stanley analyst Megan Alexander initiated coverage on the stock with an Equal-Weight rating and a price target of $27 on March 24, 2025. This analyst has an accuracy rate of 64%.</li>
<li>JP Morgan analyst Ken Goldman maintained a Neutral rating and cut the price target from $29 to $26 on March 6, 2025. This analyst has an accuracy rate of 78%.</li>
<li>Stifel analyst Matthew Smith maintained a Hold rating and cut the price target from $28 to $26 on Feb. 19, 2025. This analyst has an accuracy rate of 62%.</li>
<li>Wells Fargo analyst Chris Carey maintained an Equal-Weight rating and cut the price target from $28 to $27 on Feb. 18, 2025. This analyst has an accuracy rate of 62%.</li>
<li>B of A Securities analyst Bryan Spillane maintained a Neutral rating and cut the price target from $31 to $29 on Dec. 20, 2024. This analyst has an accuracy rate of 63%.</li>
</ul>
Considering buying CAG stock? Here&#8217;s what analysts think: 
<figure class="wp-block-image size-large is-resized"><img loading="lazy" decoding="async" width="1024" height="609" src="https://editorial-assets.benzinga.com/wp-content/uploads/2025/04/03024517/image-28-1024x609.png" alt="" class="wp-image-854594" style="width:539px;height:auto" srcset="https://editorial-assets.benzinga.com/wp-content/uploads/2025/04/03024517/image-28-1024x609.png 1024w,https://editorial-assets.benzinga.com/wp-content/uploads/2025/04/03024517/image-28-300x179.png 300w,https://editorial-assets.benzinga.com/wp-content/uploads/2025/04/03024517/image-28-768x457.png 768w,https://editorial-assets.benzinga.com/wp-content/uploads/2025/04/03024517/image-28.png 1077w" sizes="(max-width: 1024px) 100vw, 1024px" /></figure>
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Photo via Shutterstock

Conagra Brands Gears Up For Q3 Print; Here Are The Recent Forecast Changes From Wall Street's Most Accurate Analysts

Autoliv is entering two Virtual Power Purchase Agreements with the two renewable electricity producers, Alight and Eurowind Energy. They are important for ensuring a consistent and reasonably priced energy supply for Autoliv's activities in Europe, reducing the risks associated with potential future energy price fluctuations. Autoliv seeks to improve its energy resilience and ensure its operations will continue to be both economical and sustainable even in the face of volatile markets.

Autoliv Signs 12-Year Renewable Energy Agreements With Alight And Eurowind, Strengthening Energy Resilience And Climate Leadership

Mesoblast filed a request for a Type B meeting during the last quarter, in line with previous guidance, and expects to have the meeting during this quarter. The meeting will be held under Mesoblast's Regenerative Medicines Advanced Therapy (RMAT) designation for REVASCOR.
In a Type B meeting last year, FDA provided guidance to Mesoblast that the company was eligible to file for accelerated approval of REVASCOR in patients with end-stage HFrEF based on the totality of data across two randomized controlled trials. FDA also guided that a single confirmatory trial in class II/III patients with ischemic HFrEF and inflammation will need to be completed after any accelerated approval is obtained.

MESO

Reported Earlier, Mesoblast Files Type B FDA Meeting Request To Advance Revascor Toward Accelerated Approval In Ischemic Heart Failure With Inflammation

Preliminary First Quarter 2025 Results
<ul>
<li>Preliminary first quarter 2025 revenue is expected to be approximately $37.9 million, representing growth of 28% compared to the prior year period, and a decrease of 6% compared to the fourth quarter of 2024, driven by:
<ul>
<li>The sale of 27,579 Light Adjustable Lenses (LAL&#x2122;/LAL+&#xAE;); representing a 36% increase in procedure volume compared to the first quarter of 2024; and</li>
<li>The sale of 73 Light Delivery Devices (LDD&#x2122;s), bringing the installed base to 1,044 LDDs as of March 31, 2025, which represents a 43% expansion compared to the installed base of 732 LDDs at end of the first quarter of 2024</li>
</ul>
</li>
</ul>
Revised 2025 Guidance
The company decreased its 2025 full-year revenue and operating expense guidance as follows:
<ul>
<li>Revenue in the range of $160.0 million to $175.0 million, a decrease from the previous guidance range of $185.0 million to $197.0 million, representing implied growth of 14% to 25% compared to 2024;</li>
<li>Operating expenses in the range of $150.0 to $160.0 million, a decrease from the previous guidance range of $165.0 million to $170.0 million and now representing an implied increase of 10% to 18% compared to 2024;</li>
<li>Operating expenses also include non-cash stock-based compensation expense, which is now projected to be in the range of $27.0 million to $30.0 million, compared to the previous range of $22.0 million to $25.0 million.</li>
</ul>

RXST

Reported Earlier, RxSight Preliminary Q1 Results: Expects Revenue of $37.9M, Up 28% YoY (Vs. $40.14M Est.); Lowers 2025 Revenue Guidance To $160M–$175M (Vs. $188.9M Est.), Down From $185M–$197M

<ul>
<li>Vanrafia can be seamlessly added to supportive care in IgAN and used as a foundational therapy with no requirement for a REMS (Risk Evaluation Mitigation Strategy) program1</li>
<li>Phase III data showed Vanrafia achieved proteinuria reduction of 36.1% (P&lt;0.0001) vs. placebo with improvements seen at Week 6 and sustained through Week 36 and favorable safety1,2</li>
<li>IgAN is a progressive, rare kidney disease; up to 50% of patients with persistent proteinuria progress to kidney failure within 10 to 20 years of diagnosis3-9</li>
<li>With third FDA approval in under 1 year across its renal portfolio, Novartis is uniquely positioned to lead a transformation in kidney care</li>
</ul>

Reported Earlier, Novartis Gains FDA Accelerated Approval For Vanrafia, The First Selective ETA Receptor Antagonist For Proteinuria Reduction In IgA Nephropathy

Reported Earlier, Sylvan Secures Strategic Investment From Novo Holdings To Accelerate Growth, With KKR Remaining Majority Shareholder

LCID

Lucid Group Prices $1B 5.00% Convertible Senior Notes Due 2030 In Private Offering

Rilzabrutinib granted orphan drug designation in the US for two rare diseases with no approved medicines
<ul>
<li>Designation granted for warm autoimmune hemolytic anemia and IgG4-related disease</li>
<li>Rilzabrutinib is currently under regulatory review in the US, EU and China for potential use in immune thrombocytopenia&nbsp;</li>
</ul>

FDA Grants Orphan Drug Status To Sanofi's Rilzabrutinib For Two Rare Autoimmune Diseases With High Unmet Needs

President Donald Trump declared a national emergency to unveil his list of reciprocal tariffs on some of America&#8217;s biggest trade partners.
This act by the White House marks the biggest upheaval in global trade in decades, which Trump claims is being done to &#8216;strengthen the international economic position of the United States&#8217; and &#8216;protect American workers.&#8217; 
What Happened: On Wednesday, Trump invoked his authority under the International Emergency Economic Powers Act of 1977 to declare a state of emergency and enact reciprocal tariffs to address &#8216;the large and persistent trade deficit&#8217; experienced by the United States.
A <a href="https://www.whitehouse.gov/fact-sheets/2025/04/fact-sheet-president-donald-j-trump-declares-national-emergency-to-increase-our-competitive-edge-protect-our-sovereignty-and-strengthen-our-national-and-economic-security/">White House &#8216;Fact Sheet&#8217;</a> accompanying the President&#8217;s announcement lays out the list of tariffs imposed on imports into the U.S. and the countries that are being subjected to them, as Trump emphasizes the golden rule of trade: &#8216;Treat us like we treat you.&#8217;
Here&#8217;s a complete rundown of what the fact sheet entails, with a spotlight on key points and what they each mean for the U.S., as well as the global economy.
See Also: <a href="https://www.benzinga.com/markets/equities/25/04/44620686/sp-500-nasdaq-futures-plunge-over-3-as-trumps-reciprocal-tariff-plan-hits-market-confidence">Trump&#8217;s &#8216;Reciprocal Tariff&#8217; Plan Hits Market Confidence As Dow Futures Drops Over 830 Points</a>
<h3 class="wp-block-heading">1. Address Trade Deficit &amp; Unfair Practices</h3>
The fact sheet states that the <a href="https://www.wsj.com/economy/trade/us-trade-import-export-deficit-charts-490a7bce">United States suffered a $1.2 trillion trade deficit in 2024</a>, which was largely &#8216;ignored by prior leadership.&#8217; Going on to state that such persistently high deficit levels year after year are an unsustainable crisis and need to be addressed.
The <a href="https://worldpopulationreview.com/country-rankings/us-trade-deficit-by-country">countries that drive this deficit</a> include China at $270 billion, and Mexico at $160 billion, followed by Vietnam, Ireland, and Germany at $110 billion, $80 billion, and $76 billion, respectively.
It holds the pernicious economic policies and unfair trade practices of its largest partners responsible for this, highlighting the tariffs charged by countries such as India and Turkey, going as high as 60% on Apples, 70% on passenger car imports, and 80% on rice husks.
The White House says American companies are charged nearly $200 billion in value-added taxes each year by other countries, while the U.S. itself taxes little to nothing, with tariffs mostly ranging from 2.5% to 3.3%.
It further sheds light on several non-tariff barriers that leave U.S.-based companies at a disadvantage, such as Brazil and Vietnam&#8217;s restrictions on remanufactured goods.
<h3 class="wp-block-heading">2. Hollowed Out Manufacturing Base &amp; Reshoring</h3>
The fact sheet holds the country&#8217;s long-standing free-for-all trade policy responsible for the erosion of its manufacturing base. It highlights the fact that American manufacturing as a share of global output stood at 28.4% in 2001 but now stands at 17.4%.
In addition to the millions of jobs lost to this shift over the decades, the administration believes that it has left U.S. supply chains vulnerable to global shocks.
The new trade policy emphasizes the importance of reshoring manufacturing, especially in critical sectors such as defense, batteries, microelectronics, and bio-manufacturing.
<h3 class="wp-block-heading">3. Blanket Import Tariffs, Reciprocal Tariffs &amp; Exemptions</h3>
To address these challenges and more, the President used his IEEPA authority to impose a blanket 10% tariff on all goods imported into the U.S. from across the world. This is set to go into effect starting from the 5th of April 2025.
Besides this, several reciprocal tariffs are being imposed on countries with which the United States has the highest trade deficit, which is in addition to the 10% baseline. The reciprocal tariffs are set to take effect on the 9th of April 2025. For Canada and Mexico, the existing IEEPA order around fentanyl and immigration remains in effect and is unchanged.
The fact sheet outlines several products exempted from these tariffs, such as copper, pharmaceuticals, and lumber articles, alongside bullion, energy, and minerals unavailable in the United States. Steel, aluminum, auto, and auto parts are exempted, as they are part of a separate tariff order that remains in force.
Here&#8217;s the full list of reciprocal tariffs being imposed on America&#8217;s largest trading partners,
<figure class="wp-block-table"> 
<table>
<tbody>
<tr>
<td class="has-text-align-center" data-align="center">Country</td>
<td class="has-text-align-center" data-align="center">Tariffs Charged To The U.S.</td>
<td class="has-text-align-center" data-align="center">Discounted Reciprocal Tariffs</td>
</tr>
<tr>
<td class="has-text-align-center" data-align="center">China</td>
<td class="has-text-align-center" data-align="center">67%</td>
<td class="has-text-align-center" data-align="center">34%</td>
</tr>
<tr>
<td class="has-text-align-center" data-align="center">European Union</td>
<td class="has-text-align-center" data-align="center">39%</td>
<td class="has-text-align-center" data-align="center">20%</td>
</tr>
<tr>
<td class="has-text-align-center" data-align="center">Vietnam</td>
<td class="has-text-align-center" data-align="center">90%</td>
<td class="has-text-align-center" data-align="center">46%</td>
</tr>
<tr>
<td class="has-text-align-center" data-align="center">Taiwan</td>
<td class="has-text-align-center" data-align="center">64%</td>
<td class="has-text-align-center" data-align="center">32%</td>
</tr>
<tr>
<td class="has-text-align-center" data-align="center">Japan</td>
<td class="has-text-align-center" data-align="center">46%</td>
<td class="has-text-align-center" data-align="center">24%</td>
</tr>
<tr>
<td class="has-text-align-center" data-align="center">India</td>
<td class="has-text-align-center" data-align="center">52%</td>
<td class="has-text-align-center" data-align="center">26%</td>
</tr>
</tbody>
</table>
</figure>
What It Means: The tariffs do have broad implications on the U.S. and global markets, and in addition to a rout in global equity markets, analysts expect it to fuel inflation, while further increasing the risks of a recession. 
America&#8217;s trading partners are expected to respond with countermeasures, which could altogether plunge the global economy into a recession.
<h3 class="wp-block-heading">1. Trade With The United States: A &#8216;Privilege&#8217;</h3>
The President unequivocally states &#8216;Access to the American market is a privilege, not a right&#8217; and that the United States will no longer &#8216;put itself last on matters of international trade.&#8217;
According to analysts, however, this move is not without its downsides, as clamping down on the U.S. market privileges of other countries could hurt America&#8217;s biggest privilege of all, &#8216;<a href="https://thespectator.com/topic/could-trump-tariffs-damage-the-us-dollar/">The Dollar Privilege</a>&#8216;. Something that allowed it to run massive deficits and wield unprecedented geopolitical power over the decades.
<h3 class="wp-block-heading">2. Global Recession Risk</h3>
Early last month, JP Morgan Research suggested that the risk of a global recession taking hold this year was at 40%, up from 30% at the start of 2025. The analysis laid the blame squarely on the ongoing tariff war and the uncertainties surrounding the same, resulting in negative sentiments.
Now with the tariffs in place, analysts at JP Morgan are all but certain that &#8220;these policies, if sustained, would likely push the U.S. and global economy into recession this year.&#8221;
They further add that this is essentially <a href="https://edition.cnn.com/business/live-news/tariffs-trump-news-04-02-25#cm90qyswp001x3b6nd1mkndo5">a $660 billion tax on American consumers</a>, &#8216;the largest tax increase in recent memory by a longshot.&#8217;
<h3 class="wp-block-heading">3. Countermeasures By Trading Partners</h3>
Major U.S. <a href="https://in.benzinga.com/news/global/25/04/44620889/trumps-liberation-day-tariffs-roil-markets-as-china-slams-typical-unilateral-bullying-asian-markets-plunge">trade partners have begun responding to the tariffs</a>, starting with a Chinese Commerce Ministry spokesperson calling it &#8216;typical unilateral bullying&#8217; before urging the U.S. to &#8216;immediately cancel its unilateral tariff measures.&#8217;
Meanwhile, Europe joined in on condemning the tariffs, with Italian Prime Minister Giorgia Meloni calling the 20% tariffs imposed on the European Union &#8216;wrong,&#8217; followed by the Irish Taoiseach Micheál Martin, who referred to this decision as &#8216;Extremely Unsettling.&#8217;
The Indian Commerce Ministry said that it was still analyzing the impact of the 26% reciprocal tariff, with a senior official quoted as saying &#8216;a mixed bag and not a setback for India.&#8217; The Canadian Prime Minister Mark Carney, on the other hand, vowed to &#8216;act with purpose and with force.&#8217;
Image via Shutterstock
Read More: 
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<li><a href="https://www.benzinga.com/markets/equities/25/04/44620650/nvidia-amd-apple-meta-tesla-why-these-5-stocks-are-trending-on-trumps-liberation-day">Nvidia, AMD, Apple, Meta, Tesla: Why These 5 Stocks Are Trending On Trump&#8217;s Liberation Day</a></li>
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Trump Unveils Massive Tariff Plan to Slash $1.2 Trillion Trade Deficit: 'Access To The American Market Is A Privilege'

New Street Research analyst Pierre Ferragu defended his position on Wednesday that negative publicity surrounding CEO Elon Musk won&#8217;t harm Tesla Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/TSLA#NASDAQ">TSLA</a>) in the medium term.
What Happened: &#8220;Many question our view that &#8216;bad press&#8217; related to Elon will not have a lasting influence on Tesla sales,&#8221; Ferragu wrote on X. &#8220;Elon&#8217;s antics are very unlikely to damage the brand medium term (and they definitely help awareness!!).&#8221;
The analyst shared data showing significant drops in Tesla&#8217;s brand perception during 2022, including a 21-point decline in March and a 17-point drop in November, coinciding with Musk&#8217;s Twitter acquisition. Despite these metrics, Tesla&#8217;s quarterly deliveries grew steadily from 185,000 in the first quarter of 2021 to 485,000 by the fourth quarter of 2023.
Ferragu&#8217;s optimistic assessment comes amid recent challenges for the automaker. Tesla reported approximately 337,000 vehicle deliveries in the first quarter of 2025, falling short of analyst expectations across all major markets. The disappointing results sent shares tumbling <a href="https://www.benzinga.com/analyst-ratings/analyst-color/25/04/44612478/musk-needs-to-navigate-brand-crisis-or-else-warns-analyst-tesla-delivery-number-was-a-disaster-for-the-bulls">before recovering Wednesday</a>.
<figure class="wp-block-embed is-type-rich is-provider-twitter wp-block-embed-twitter"> 
<div class="wp-block-embed__wrapper">
<blockquote class="twitter-tweet" data-width="500" data-dnt="true">Many question our view that &quot;bad press&quot; related to Elon will not have a lasting influence on Tesla sales. Here is our underlying analysis. Elon&#39;s antics are very unlikely to damage the brand medium term (and they definitely help awareness!!) <a href="https://t.co/fsYL53GtDE">pic.twitter.com/fsYL53GtDE</a>
&mdash; Pierre Ferragu (@p_ferragu) <a href="https://twitter.com/p_ferragu/status/1907579341149737344?ref_src=twsrc%5Etfw">April 2, 2025</a></blockquote>
<script async src="https://platform.twitter.com/widgets.js" charset="utf-8"></script></div>
</figure>
See Also: <a href="https://www.benzinga.com/news/global/25/04/44620889/trumps-liberation-day-tariffs-roil-markets-as-china-slams-typical-unilateral-bullying-asian-markets-plunge">Trump&#8217;s &#8216;Liberation Day&#8217; Tariffs Roil Markets As China Slams &#8216;Typical Unilateral Bullying:&#8217; Asian Markets Plunge</a>
Why It Matters: Wedbush Securities analyst Dan Ives called the figures &#8220;a disaster for the bulls&#8221; while maintaining an Outperform rating with a $550 price target. &#8220;The more political he gets with DOGE, the more the brand suffers, there is no debate,&#8221; Ives said, <a href="https://www.benzinga.com/analyst-ratings/analyst-color/25/04/44612478/musk-needs-to-navigate-brand-crisis-or-else-warns-analyst-tesla-delivery-number-was-a-disaster-for-the-bulls">referring to Musk&#8217;s role</a> in the Department of Government Efficiency under President Donald Trump&#8216;s administration.
Tesla stock rebounded over 5% in regular session on Wednesday following a Politico report suggesting Musk might <a href="https://www.benzinga.com/markets/equities/25/04/44617674/tesla-closes-in-green-dips-after-hours-as-musk-denies-ouster-from-trump-administration">step back from his government position in the coming weeks</a>. Musk dismissed the report as &#8220;fake news&#8221; on X, after which shares dipped 8.01% in after-hours trading.
The company&#8217;s stock has fallen as much as 33% since Trump&#8217;s January inauguration, with analysts attributing some decline to <a href="https://www.benzinga.com/markets/equities/25/04/44617674/tesla-closes-in-green-dips-after-hours-as-musk-denies-ouster-from-trump-administration">Musk&#8217;s political activities</a>, including his reported $20 million investment to defeat a Wisconsin Supreme Court candidate and endorsements of far-right parties in Europe.
Price Action: Tesla closed at $282.76 on Wednesday, gaining 5.33% for the day. In after-hours trading, the stock declined 8.01% to $260.12.
Tesla stock has outperformed rivals Nio Inc. (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/NIO#NYSE">NIO</a>) and Lucid Group Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/LCID#NASDAQ">LCID</a>) but trails Rivian Automotive Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/RIVN#NASDAQ">RIVN</a>) in short- to long-term price trends, according to Benzinga Edge Stock Ranking. <a href="https://www.benzinga.com/premium/ideas/benzinga-edge-2#:~:text=Turn%20Market%20Chaos,when%20markets%20rebound">Sign up to learn more</a>.
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Image via Shutterstock
Disclaimer:&nbsp;This content was partially produced with the help of AI tools and was reviewed and published by Benzinga editors.

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Gold prices hit a new all-time high Wednesday as investors sought refuge in the safe haven following President Donald Trump&#8217;s sweeping tariffs that sent risk-on markets falling.
What happened: Spot gold rose 0.46% to $3,148.93 per ounce as of this writing, down slightly from the peak of $3,167 recorded earlier in the day. Gold futures on the Commodity Exchange were up 0.15% to $3,171.&nbsp;
With the latest uptick, the yellow metal extended its year-to-date gains to 20%.
The rise also boosted physical gold-backed cryptocurrencies. Tether Gold and PAX Gold rose 1.02% in the last 24 hours and over 20% since 2025 began.
In fact, the two cryptocurrency derivatives of gold were among the five most successful coins this year, far outperforming heavyweights like Bitcoin (CRYPTO: <a class="ticker" href="https://www.benzinga.com/quote/btc/usd">BTC</a>) and Ethereum (CRYPTO: <a class="ticker" href="https://www.benzinga.com/quote/eth/usd">ETH</a>).
<figure class="wp-block-table"> 
<table>
<tbody>
<tr>
<td>Cryptocurrency</td>
<td>24-Hour Gains +/-</td>
<td>YTD Gains +/-</td>
<td>Price (Recorded at 12:30 a.m. ET)</td>
</tr>
<tr>
<td>PAX Gold (CRYPTO: <a class="ticker" href="https://www.benzinga.com/quote/paxg/usd">PAXG</a>)</td>
<td>+1.02%</td>
<td>+20.16%</td>
<td>$3,167.24</td>
</tr>
<tr>
<td>Tether Gold (CRYPTO: XAUT)</td>
<td>+1.02%</td>
<td>+20.93%</td>
<td>$3,171.20</td>
</tr>
</tbody>
</table>
</figure>
See Also:<a href="https://www.benzinga.com/24/12/42735744/pharma-bro-martin-shkreli-predicts-doom-for-michael-saylors-microstrategy-as-stock-dips-below-300-in-after-hours-trading"> </a><a href="https://www.benzinga.com/25/03/44555553/will-the-greatest-of-them-all-trump-memecoin-make-its-way-to-trump-media-etfs-polymarket-bettors-think-its-unlikely">&#8216;Greatest Of Them All&#8217; TRUMP Memecoin Headed for Trump Media ETFs? Polymarket Bettors Think It&#8217;s Unlikely</a>
Well-known cryptocurrency analyst Ali Martinez stated that DOGE was at a "make-or-break level."
"If $0.16 holds, a rally to $0.57 could follow. If it fails, a drop to $0.06 becomes likely," the analyst projected.
Gold bug and renowned economist Peter Schiff called gold a "true safe haven and store of value," while highlighting the fall of Bitcoin, considered by some as a "digital gold."
<figure class="wp-block-embed is-type-rich is-provider-twitter wp-block-embed-twitter"> 
<div class="wp-block-embed__wrapper">
<blockquote class="twitter-tweet" data-width="500" data-dnt="true">Bitcoin is now leading risk assets lower. It&#39;s already down 7% from the high that it hit shortly after Trump began his Liberation Day speech. Meanwhile, gold, a true safe haven and store of value, is up another $30, trading in new record territory above $3,160.
&mdash; Peter Schiff (@PeterSchiff) <a href="https://twitter.com/PeterSchiff/status/1907585940115132685?ref_src=twsrc%5Etfw">April 3, 2025</a></blockquote>
<script async src="https://platform.twitter.com/widgets.js" charset="utf-8"></script></div>
</figure>
Capital markets tumbled after the scope and scale of Trump's new reciprocal tariff structure <a href="https://www.benzinga.com/government/regulations/25/04/44618089/trumps-tariffs-surprise-triggers-carnage-magnificent-7-set-to-wipe-out-nearly-700-billion-">exceeded Wall Street's worst-case expectations</a>. The new levies on imported goods would be set at 50% of what the trading partners charge the U.S.
Image via Shutterstock
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