Spruce Biosciences (OTC:SPRB) Stock

SPRUCE BIOSCIENCES INC

Spruce Biosciences

Spruce Biosciences Inc is a late-stage biopharmaceutical company focused on developing and commercializing novel therapies for rare endocrine disorders with unmet medical needs. The pipeline products of the company include Tralesinidase Alfa (TA-ERT), and Tildacerfont/ Cortibon, a Companion Diagnostic, developed in partnership with HMNC Brain Health.

SPRUCE BIOSCIENCES INC by Spruce Biosciences, Inc.

Spruce Biosciences Inc

SPAREBANKEN 1 OSTLANDET by Sparebank 1 Ostlandet

Spruce Biosciences (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/SPRB#NASDAQ">SPRB</a>) reported quarterly losses of $(0.32) per share which missed the analyst consensus estimate of $(0.22) by 45.45 percent. This is a 14.29 percent decrease over losses of $(0.28) per share from the same period last year.

Earnings

Earnings Misses

News

SPRB

Spruce Biosciences Q1 GAAP EPS $(0.32) Misses $(0.22) Estimate

<h3>Gainers</h3>
<ul>
<li>LogicMark (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/LGMK#NASDAQ">LGMK</a>) shares increased by 34.5% to $0.01 during Monday's regular session. </li>
<li>CG Oncology (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/CGON#NASDAQ">CGON</a>) shares moved upwards by 32.81% to $29.71. The market value of their outstanding shares is at $2.2 billion. </li>
<li>Zhengye Biotechnology (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/ZYBT#NASDAQ">ZYBT</a>) stock rose 32.18% to $13.8. The company's market cap stands at $654.0 million. </li>
<li>iBio (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/IBIO#NASDAQ">IBIO</a>) shares moved upwards by 30.56% to $1.2. The company's market cap stands at $11.8 million. </li>
<li>Gelteq (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/GELS#NASDAQ">GELS</a>) shares increased by 24.21% to $2.36. The company's market cap stands at $22.2 million. </li>
<li>Brainstorm Cell (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/BCLI#NASDAQ">BCLI</a>) shares moved upwards by 24.0% to $1.21. The company's market cap stands at $6.8 million. </li>
</ul>
<h3>Losers</h3>
<ul>
<li>Spruce Biosciences (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/SPRB#NASDAQ">SPRB</a>) shares fell 26.2% to $0.1 during Monday's regular session. The company's market cap stands at $3.9 million. </li>
<li>SILO Pharma (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/SILO#NASDAQ">SILO</a>) stock fell 22.6% to $0.89. The company's market cap stands at $3.9 million. </li>
<li>Senti Biosciences (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/SNTI#NASDAQ">SNTI</a>) shares decreased by 20.8% to $3.96. The market value of their outstanding shares is at $102.9 million. </li>
<li>Abpro Hldgs (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/ABP#NASDAQ">ABP</a>) stock fell 18.94% to $0.26. The market value of their outstanding shares is at $13.4 million. </li>
<li>Healthcare Triangle (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/HCTI#NASDAQ">HCTI</a>) shares decreased by 18.74% to $0.15. The company's market cap stands at $6.7 million. </li>
<li>Protara Therapeutics (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/TARA#NASDAQ">TARA</a>) stock declined by 18.52% to $3.52. The company's market cap stands at $129.4 million. 
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</ul>
This article was generated by Benzinga's automated content engine and reviewed by an editor.

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12 Health Care Stocks Moving In Monday's Intraday Session

U.S. stocks traded lower midway through trading, with the Nasdaq Composite falling around 200 points on Monday.
The Dow traded down 0.27% to 40,004.11 while the NASDAQ fell 1.19% to 17,175.43. The S&amp;P 500 also fell, dropping, 0.72% to 5,485.36.
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Leading and Lagging Sectors Financial shares jumped by 0.6% on Monday.
In trading on Monday, information technology fell by 0.6%.
Top Headline
Roper Technologies, Inc (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/ROP#NASDAQ">ROP</a>) reported better-than-expected earnings for its first quarter and raised its forecast.
The company posted first-quarter adjusted earnings per share of $4.78, beating the street view of $4.74. Quarterly sales of $1.88 billion outpaced the analyst consensus estimate of $1.82 billion.
Roper Technologies expects fiscal 2025 adjusted earnings per share of $19.80-$20.05 (compared to a previous outlook of $19.75-$20.00), versus the $19.92 estimate. It increased its full-year total revenue growth outlook to ~12% or $7.88 billion (compared to a previous outlook of 10%+ or $7.74 billion) and an analyst estimate of $7.74 billion. It reiterated organic revenue growth of +6-7%.
Equities Trading UP &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
<ul>
<li>Galmed Pharmaceuticals Ltd. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/GLMD#NASDAQ">GLMD</a>) shares shot up 46% to $2.2999. Galmed signed a term sheet for the development of novel semaglutide sublingual formulation.</li>
<li>Shares of CG Oncology, Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/CGON#NASDAQ">CGON</a>)got a boost, surging 31% to $29.21 after the company announced that cretostimogene grenadenorepvec monotherapy data was presented at the American Urological Association Annual Meeting.</li>
<li>Plug Power Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/PLUG#NASDAQ">PLUG</a>) shares were also up, gaining 42% to $1.15 after the company signed a secured credit facility with Yorkville Advisors. The company also reported preliminary first-quarter results.</li>
</ul>
Equities Trading DOWN
<ul>
<li>Spruce Biosciences, Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/SPRB#NASDAQ">SPRB</a>) shares dropped 28% to $0.0935 after the company announced it approved a plan to implement a workforce reduction.</li>
<li>Shares of Groupon, Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/GRPN#NASDAQ">GRPN</a>) were down 15% to $16.86.</li>
<li>Protara Therapeutics, Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/TARA#NASDAQ">TARA</a>) was down, falling 19% to $3.4899 as the company announced interim results highlighting durable clinical responses with TARA-002 In high-risk NMIBC.</li>
</ul>
Commodities In commodity news, oil traded down 2% to $61.78 while gold traded up 0.6% at $3,316.80.
Silver traded down 0.5% to $32.845 on Monday, while copper rose 0.1% to $4.90.
Euro zone
European shares were higher today. The eurozone's STOXX 600 gained 0.74%, Germany's DAX 40 gained 0.67% and France's CAC 40 gained 0.87%. Spain's IBEX 35 Index gained 0.81%, while London's FTSE 100 rose 0.30%.
Asia Pacific Markets
Asian markets closed mixed on Monday, with Japan's Nikkei 225 surging 0.38%, China's Shanghai Composite falling 0.20%, Hong Kong's Hang Seng Index falling 0.04% and India's BSE Sensex gaining 1.27%.
Economics
The Dallas Fed manufacturing index will be released today.
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</ul>
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Equities

Eurozone

Commodities

Intraday Update

Markets

GLMD

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Crude Oil Down 2%; Roper Technologies Increases 2025 Outlook

U.S. stocks traded higher this morning, with the Dow Jones index gaining more than 150 points on Monday.
Following the market opening Monday, the Dow traded up 0.47% to 40,300.68 while the NASDAQ rose 0.13% to 17,405.94. The S&amp;P 500 also rose, gaining, 0.31% to 5,542.29.
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Leading and Lagging Sectors Industrials shares jumped by 0.7% on Monday.
In trading on Monday, information technology fell by 0.4%.
Top Headline
Domino&#8217;s Pizza, Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/DPZ#NASDAQ">DPZ</a>) reported better-than-expected earnings for its first quarter on Monday.
The company posted quarterly earnings of $4.33 per share which beat the analyst consensus estimate of $4.07 per share. The company reported quarterly sales of $1.11 billion which missed the analyst consensus estimate of $1.13 billion.
Equities Trading UP &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
<ul>
<li>Galmed Pharmaceuticals Ltd. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/GLMD#NASDAQ">GLMD</a>) shares shot up 47% to $2.32. Galmed signed a term sheet for the development of novel semaglutide sublingual formulation.</li>
<li>Shares of CG Oncology, Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/CGON#NASDAQ">CGON</a>)got a boost, surging 36% to $30.47 after the company announced that cretostimogene grenadenorepvec monotherapy data was presented at the American Urological Association Annual Meeting.</li>
<li>NaaS Technology Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/NAAS#NASDAQ">NAAS</a>) shares were also up, gaining 53% to $2.75. NaaS Technology, last week, announced a 1-for-800 ADS ratio change.</li>
</ul>
Equities Trading DOWN
<ul>
<li>Spruce Biosciences, Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/SPRB#NASDAQ">SPRB</a>) shares dropped 31% to $0.09 after the company announced it approved a plan to implement a workforce reduction.</li>
<li>Shares of Pineapple Financial Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/PAPL#NASDAQ">PAPL</a>) were down 17% to $0.2241.</li>
<li>Protara Therapeutics, Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/TARA#NASDAQ">TARA</a>) was down, falling 24% to $3.30 as the company announced interim results highlighting durable clinical responses with TARA-002 In high-risk NMIBC.</li>
</ul>
Commodities In commodity news, oil traded down 0.2% to $62.92 while gold traded up 0.3% at $3,306.70.
Silver traded down 0.3% to $32.91 on Monday, while copper rose 0.4% to $4.9120.
Euro zone
European shares were higher today. The eurozone's STOXX 600 gained 0.7%, Germany's DAX 40 gained 0.7% and France's CAC 40 gained 1%. Spain's IBEX 35 Index gained 0.7%, while London's FTSE 100 rose 0.4%.
Asia Pacific Markets
Asian markets closed mixed on Monday, with Japan's Nikkei 225 surging 0.38%, China's Shanghai Composite falling 0.20%, Hong Kong's Hang Seng Index falling 0.04% and India's BSE Sensex gaining 1.27%.
Economics
The Dallas Fed manufacturing index will be released today.
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</ul>
Photo via Shutterstock

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<h3>Gainers</h3>
<ul>
<li>Portage Biotech (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/PRTG#NASDAQ">PRTG</a>) shares increased by 49.2% to $12.61 during Monday's pre-market session. The market value of their outstanding shares is at $20.7 million. </li>
<li>CG Oncology (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/CGON#NASDAQ">CGON</a>) stock rose 43.49% to $32.1. The company's market cap stands at $2.4 billion. </li>
<li>Bionano Genomics (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/BNGO#NASDAQ">BNGO</a>) stock rose 30.93% to $5.63. The market value of their outstanding shares is at $15.3 million. </li>
<li>Tharimmune (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/THAR#NASDAQ">THAR</a>) shares moved upwards by 23.34% to $1.48. The market value of their outstanding shares is at $2.8 million. </li>
<li>Autonomix Medical (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/AMIX#NASDAQ">AMIX</a>) shares increased by 16.78% to $2.43. The market value of their outstanding shares is at $5.9 million. </li>
<li>60 Degrees (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/SXTP#NASDAQ">SXTP</a>) shares moved upwards by 12.54% to $3.32. The company's market cap stands at $4.8 million. </li>
</ul>
<h3>Losers</h3>
<ul>
<li>Spruce Biosciences (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/SPRB#NASDAQ">SPRB</a>) shares fell 32.7% to $0.09 during Monday's pre-market session. The market value of their outstanding shares is at $3.6 million. </li>
<li>Inspire Veterinary (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/IVP#NASDAQ">IVP</a>) stock declined by 22.09% to $1.27. The company's market cap stands at $1.8 million. </li>
<li>Zynex (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/ZYXI#NASDAQ">ZYXI</a>) shares declined by 14.94% to $2.05. The market value of their outstanding shares is at $61.9 million. </li>
<li>Salarius Pharmaceuticals (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/SLRX#NASDAQ">SLRX</a>) stock decreased by 12.66% to $0.64. The company's market cap stands at $1.3 million. </li>
<li>Abpro Hldgs (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/ABP#NASDAQ">ABP</a>) shares declined by 12.62% to $0.28. The company's market cap stands at $14.5 million. </li>
<li>Upstream Bio (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/UPB#NASDAQ">UPB</a>) shares declined by 9.3% to $7.61. The company's market cap stands at $408.5 million. 
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</ul>
This article was generated by Benzinga's automated content engine and reviewed by an editor.

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12 Health Care Stocks Moving In Monday's Pre-Market Session

HC Wainwright &amp; Co. analyst Raghuram Selvaraju reiterates Spruce Biosciences (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/SPRB#NASDAQ">SPRB</a>) from Neutral to Neutral.

Reiteration

Analyst Ratings

HC Wainwright & Co. Reiterates Neutral on Spruce Biosciencesto Neutral

WIIM

Spruce Biosciences shares are trading lower after the company announced it approved a plan to implement a workforce reduction.

Shares of Amplify Energy Corp. (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/AMPY#NYSE">AMPY</a>) rose sharply in today's pre-market after the company announced its termination of the previously announced merger agreement <a href="https://www.benzinga.com/quote/AMPY">with Juniper Capital</a>.
Amplify Energy shares jumped 15.5% to $3.11 in pre-market trading
Here are some other stocks moving in pre-market trading.
<h3 class="wp-block-heading">Gainers</h3>
<ul>
<li>AGM Group Holdings Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/AGMH#NASDAQ">AGMH</a>) rose 47% to $0.0714 in pre-market trading after gaining around 25% on Friday.</li>
<li>Xunlei Limited (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/XNET#NASDAQ">XNET</a>) surged 17.8% to $4.57 in pre-market trading after falling 5% on Friday.</li>
<li>Aurora Innovation, Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/AUR#NASDAQ">AUR</a>) surged 15.1% to $7.92 in pre-market trading.</li>
<li>QuantaSing Group Limited (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/QSG#NASDAQ">QSG</a>) gained 13.1% to $5.70 in pre-market trading.</li>
<li>Faraday Future Intelligent Electric Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/FFAI#NASDAQ">FFAI</a>) gained 12.4% to $1.18 in pre-market trading. Faraday Future received powerful endorsements from California leaders backing FX brand, Bridge strategy, and YT Jia&#8217;s co-CEO appointment.</li>
<li>CPI Aerostructures, Inc. (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/CVU#NYSE">CVU</a>) jumped 12.4% to $3.72 in pre-market trading.</li>
<li>Safe Bulkers, Inc. (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/SB#NYSE">SB</a>) rose 10.3% to $3.74 in pre-market trading a.</li>
<li>UMH Properties, Inc. (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/UMH#NYSE">UMH</a>) gained 9.8% to $19.19 in pre-market trading.</li>
<li>BigBear.ai Holdings, Inc. (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/BBAI#NYSE">BBAI</a>) shares jumped 8.8% to $3.84 in pre-market trading after jumping 21% on Friday.</li>
</ul>
<h3 class="wp-block-heading">Losers</h3>
<ul>
<li>Spruce Biosciences, Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/SPRB#NASDAQ">SPRB</a>) shares fell 39.1% to $0.0790 in pre-market trading. Spruce Biosciences approved a plan to implement a workforce reduction of 55% on April 21, 2025, effective immediately.</li>
<li>Baijiayun Group Ltd (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/RTC#NASDAQ">RTC</a>) shares dipped 18.9% to $0.2640 in pre-market trading. Baijiayun shares surged around 75% on Friday after the company announced a multi-year investment plan to build a new ecosystem for autism rehabilitation.</li>
<li>Methode Electronics, Inc. (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/MEI#NYSE">MEI</a>) declined 17.6% to $5.26 in pre-market trading.</li>
<li>Odyssey Marine Exploration, Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/OMEX#NASDAQ">OMEX</a>) shares tumbled 15.9% to $1.27 in pre-market trading. Odyssey Marine Exploration shares surged 77% on Friday amid President Trump&#8217;s plans to advance the deep sea mining industry.</li>
<li>Jiuzi Holdings, Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/JZXN#NASDAQ">JZXN</a>) fell 14.6% to $2.53 in pre-market trading after gaining 25% on Friday.</li>
<li>Health Catalyst, Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/HCAT#NASDAQ">HCAT</a>) fell 14.4% to $3.51 in pre-market trading. Citigroup, on Friday, maintained a Buy rating on Health Catalyst and lowered the price target to $6.5.</li>
<li>Viemed Healthcare, Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/VMD#NASDAQ">VMD</a>) shares fell 13.5% to $6.12 in pre-market trading. Viemed Healthcare will host its first quarter earnings conference call on Thursday, May 8.</li>
<li>Abpro Corporation (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/ABP#NASDAQ">ABP</a>) dipped 13.2% to $0.2760 in pre-market trading. Abpro and Celltrion presented preclinical data for ABP-102/CT-P72, showcasing potential best-in-class HER2 X CD3 T-cell engager.</li>
<li>RXO, Inc. (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/RXO#NYSE">RXO</a>) fell 10.7% to $12.01 in pre-market trading. Truist Securities analyst Lucas Servera, on April 24, maintained RXO with a Buy and lowered the price target from $24 to $19.</li>
<li>The ODP Corporation (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/ODP#NASDAQ">ODP</a>) fell 9.8% to $12.01 in today's pre-market trading. ODP will announce first quarter financial results before the opening bell on Wednesday, May 7.</li>
</ul>
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Faraday Future Intelligent Electric Inc. - Class A Common Stock

FFAI

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Why Amplify Energy Shares Are Trading Higher By Over 15%; Here Are 20 Stocks Moving Premarket

General

Spruce Biosciences Approved A Plan To Implement A Workforce Reduction Of 55% On April 21, 2025, Effective Immediately

RBC Capital analyst Gregory Renza maintains Spruce Biosciences (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/SPRB#NASDAQ">SPRB</a>) with a Sector Perform and lowers the price target from $1.5 to $0.5.

Price Target

RBC Capital Maintains Sector Perform on Spruce Biosciences, Lowers Price Target to $0.5

<h3>Gainers</h3>
<ul>
<li>Mural Oncology (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/MURA#NASDAQ">MURA</a>) stock increased by 145.5% to $2.53 during Tuesday's regular session. The market value of their outstanding shares is at $43.5 million. </li>
<li>Skye Bioscience (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/SKYE#NASDAQ">SKYE</a>) stock moved upwards by 36.64% to $1.79. The market value of their outstanding shares is at $55.4 million. </li>
<li>Dogwood Therapeutics (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/DWTX#NASDAQ">DWTX</a>) stock moved upwards by 32.57% to $3.98. The company's market cap stands at $7.6 million. </li>
<li>Phio Pharma (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/PHIO#NASDAQ">PHIO</a>) shares increased by 29.47% to $2.85. The market value of their outstanding shares is at $13.6 million. </li>
<li>Verve Therapeutics (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/VERV#NASDAQ">VERV</a>) shares increased by 24.51% to $5.13. The company's market cap stands at $455.5 million. </li>
<li>Aptorum Gr (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/APM#NASDAQ">APM</a>) stock rose 21.12% to $0.99. The company's market cap stands at $7.0 million. </li>
</ul>
<h3>Losers</h3>
<ul>
<li>Spruce Biosciences (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/SPRB#NASDAQ">SPRB</a>) stock declined by 55.9% to $0.14 during Tuesday's regular session. The market value of their outstanding shares is at $5.7 million. The company's, Q4 earnings came out today. </li>
<li>MetaVia (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/MTVA#NASDAQ">MTVA</a>) stock declined by 37.78% to $1.15. The company's market cap stands at $9.9 million. </li>
<li>MSP Recovery (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/MSPR#NASDAQ">MSPR</a>) shares decreased by 22.27% to $2.2. The market value of their outstanding shares is at $4.6 million. </li>
<li>Impact BioMedical (AMEX:<a class="ticker" href="https://www.benzinga.com/stock/IBO#AMEX">IBO</a>) shares declined by 22.26% to $0.37. The market value of their outstanding shares is at $4.2 million. </li>
<li>Geovax Labs (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/GOVX#NASDAQ">GOVX</a>) shares decreased by 21.73% to $0.84. The company's market cap stands at $7.9 million. </li>
<li>Sharps Technology (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/STSS#NASDAQ">STSS</a>) stock fell 19.3% to $0.03. 
See Also: <a href="http://www.benzinga.com/money/best-healthcare-stocks/" title="www.benzinga.com/money/best-healthcare-stocks/">www.benzinga.com/money/best-healthcare-stocks/</a></li>
</ul>
This article was generated by Benzinga's automated content engine and reviewed by an editor.

DWTX

GOVX

MSPR

MTVA

MURA

PHIO

SKYE

STSS

VERV

12 Health Care Stocks Moving In Tuesday's Intraday Session

U.S. stocks traded higher midway through trading, with the Dow Jones  index gaining around 50 points on Tuesday.
The Dow traded up 0.17% to 40,592.77 while the NASDAQ gained 0.39% to 16,896.58. The S&amp;P 500 also rose, gaining, 0.35% to 5,424.63.
Check This Out: <a href="https://www.benzinga.com/news/earnings/25/04/44811469/how-to-earn-500-a-month-from-abbott-laboratories-stock-ahead-of-q1-earnings">How To Earn $500 A Month From Abbott Laboratories Stock Ahead Of Q1 Earnings</a>
Leading and Lagging Sectors Financial shares surged by 1.2% on Tuesday.
In trading on Tuesday, health care shares fell by 0.3%.
Top Headline
Citigroup Inc. (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/C#NYSE">C</a>) posted better-than-expected earnings for its first quarter.
Citigroup reported quarterly earnings of $1.96 per share which beat the analyst consensus estimate of $1.84 per share. The company reported quarterly sales of $21.60 billion which beat the analyst consensus estimate of $21.29 billion.
Equities Trading UP &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
<ul>
<li>Mural Oncology plc (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/MURA#NASDAQ">MURA</a>) shares shot up 146% to $2.5299 after the company announced plans to explore strategic alternatives and discontinue clinical development of nemvaleukin.</li>
<li>Shares of Skye Bioscience, Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/SKYE#NASDAQ">SKYE</a>)got a boost, surging 51% to $1.98 after the company reported weight loss results from its Nimacimab and Tirzepatide preclinical obesity model.</li>
<li>Rezolve AI PLC (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/RZLV#NASDAQ">RZLV</a>) shares were also up, gaining 24% to $1.4160 as the company announced a $9.8 million yearly contract with Liverpool Mexico.</li>
</ul>
Equities Trading DOWN
<ul>
<li>Spruce Biosciences, Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/SPRB#NASDAQ">SPRB</a>) shares dropped 59% to $0.1299 as the company announced new corporate strategy and acquisition of Tralesinidase Alfa for the treatment of Sanfilippo Syndrome Type B (MPS IIIB).</li>
<li>Shares of GeoVax Labs, Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/GOVX#NASDAQ">GOVX</a>) were down 31% to $0.7439 after multiple firms cut their respective price targets on the stock.</li>
<li>Applied Digital Corporation (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/APLD#NASDAQ">APLD</a>) was down, falling 27% to $3.9207 following weak quarterly revenue.</li>
</ul>
Commodities In commodity news, oil traded down 0.8% to $61.02 while gold traded up 0.4% at $3,237.90.
Silver traded up 0.1% to $32.180 on Tuesday, while copper fell 0.5% to $4.6015.
Euro zone
European shares were higher today. The eurozone's STOXX 600 jumped 1.69%, Germany's DAX 40 gained 1.51% and France's CAC 40 climbed 0.96%. Spain's IBEX 35 Index surged 2.09%, while London's FTSE 100 rose 1.45%.
Asia Pacific Markets
Asian markets closed higher on Tuesday, with Japan's Nikkei 225 gaining 0.84%, China's Shanghai Composite gaining 0.15%, Hong Kong's Gang Seng index rising 0.23% and India's BSE Sensex gaining 2.1%.
Economics
<ul>
<li>The NY Empire State Manufacturing Index climbed to -8.1 in April compared to -20 in the previous month.</li>
<li>U.S. export prices came in unchanged in March compared to a revised 0.5% gain in February.</li>
<li>U.S. import prices fell by 0.1% in March 2025 compared to a revised 0.2% gain in February.</li>
</ul>
Now Read This:
<ul>
<li> <a href="https://www.benzinga.com/markets/25/04/44811698/jim-cramer-planet-fitness-is-doing-better-than-expected-says-no-to-this-industrial-stock">Jim Cramer: Planet Fitness Is Doing Better Than Expected, Says No To This Industrial Stock</a></li>
</ul>
Photo via Shutterstock

APLD

RZLV

Crude Oil Moves Lower; Citigroup Posts Upbeat Results

Spruce Biosciences shares are trading lower. The company announced a new corporate strategy and acquisition of tralesinidase alfa enzyme replacement therapy for the treatment of Sanfilippo Syndrome Type B.

U.S. stocks traded higher this morning, with the Nasdaq Composite gaining around 100 points on Tuesday.
Following the market opening Tuesday, the Dow traded up 0.41% to 40,689.26 while the NASDAQ gained 0.60% to 16,932.04. The S&amp;P 500 also rose, gaining, 0.55% to 5,435.97.
Check This Out: <a href="https://www.benzinga.com/news/earnings/25/04/44811469/how-to-earn-500-a-month-from-abbott-laboratories-stock-ahead-of-q1-earnings">How To Earn $500 A Month From Abbott Laboratories Stock Ahead Of Q1 Earnings</a>
Leading and Lagging Sectors Financial shares surged by 1.3% on Tuesday.
In trading on Tuesday, health care shares fell by 0.3%.
Top Headline
Bank of America Corporation (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/BAC#NYSE">BAC</a>) posted better-than-expected earnings for its first quarter.
Bank of America reported quarterly earnings of 90 cents per share which beat the analyst consensus estimate of 81 cents per share. The company reported quarterly sales of $27.40 billion which beat the analyst consensus estimate of $26.99 billion.
Equities Trading UP &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
<ul>
<li>Mural Oncology plc (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/MURA#NASDAQ">MURA</a>) shares shot up 139% to $2.46 after the company announced plans to explore strategic alternatives and discontinue clinical development of nemvaleukin.</li>
<li>Shares of Skye Bioscience, Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/SKYE#NASDAQ">SKYE</a>)got a boost, surging 119% to $2.8699 after the company reported weight loss results from its Nimacimab and Tirzepatide preclinical obesity model.</li>
<li>Synergy CHC Corp. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/SNYR#NASDAQ">SNYR</a>) shares were also up, gaining 71% to $3.0550.</li>
</ul>
Equities Trading DOWN
<ul>
<li>Spruce Biosciences, Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/SPRB#NASDAQ">SPRB</a>) shares dropped 58% to $0.1327 as the company announced new corporate strategy and acquisition of Tralesinidase Alfa for the treatment of Sanfilippo Syndrome Type B (MPS IIIB).</li>
<li>Shares of GeoVax Labs, Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/GOVX#NASDAQ">GOVX</a>) were down 27% to $0.7768 after multiple firms cut their respective price targets on the stock.</li>
<li>Webull Corporation (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/BULL#NASDAQ">BULL</a>) was down, falling 19% to $50.71.</li>
</ul>
Commodities In commodity news, oil traded up 0.2% to $61.64 while gold traded up 0.1% at $3,229.40.
Silver traded up 0.2% to $32.215 on Tuesday, while copper fell 0.5% to $4.6015.
Euro zone
European shares were higher today. The eurozone's STOXX 600 jumped 1.5%, Germany's DAX 40 gained 1.4% and France's CAC 40 climbed 0.7%. Spain's IBEX 35 Index surged 2%, while London's FTSE 100 rose 1.2%.
Asia Pacific Markets
Asian markets closed higher on Tuesday, with Japan's Nikkei 225 gaining 0.84%, China's Shanghai Composite gaining 0.15%, Hong Kong's Gang Seng index rising 0.23% and India's BSE Sensex gaining 2.1%.
Economics
<ul>
<li>The NY Empire State Manufacturing Index climbed to -8.1 in April compared to -20 in the previous month.</li>
<li>U.S. export prices came in unchanged in March compared to a revised 0.5% gain in February.</li>
<li>U.S. import prices fell by 0.1% in March 2025 compared to a revised 0.2% gain in February.</li>
</ul>
Now Read This: 
<ul>
<li><a href="https://www.benzinga.com/markets/25/04/44811698/jim-cramer-planet-fitness-is-doing-better-than-expected-says-no-to-this-industrial-stock">Jim Cramer: Planet Fitness Is Doing Better Than Expected, Says No To This Industrial Stock</a></li>
</ul>
Photo via Shutterstock

BULL

SNYR

Nasdaq Surges 100 Points; Bank of America Earnings Top Views

<h3>Gainers</h3>
<ul>
<li>Mural Oncology (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/MURA#NASDAQ">MURA</a>) shares increased by 31.1% to $1.35 during Tuesday's pre-market session. The company's market cap stands at $23.2 million. </li>
<li>Ensysce Biosciences (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/ENSC#NASDAQ">ENSC</a>) stock rose 20.36% to $2.36. The company's market cap stands at $3.3 million. </li>
<li>OneMedNet (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/ONMD#NASDAQ">ONMD</a>) shares rose 17.36% to $0.58. The market value of their outstanding shares is at $16.2 million. </li>
<li>Fractyl Health (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/GUTS#NASDAQ">GUTS</a>) stock rose 15.61% to $1.15. The company's market cap stands at $55.3 million. </li>
<li>MetaVia (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/MTVA#NASDAQ">MTVA</a>) shares increased by 14.13% to $2.1. The company's market cap stands at $18.1 million. </li>
<li>Precision BioSciences (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/DTIL#NASDAQ">DTIL</a>) shares increased by 12.73% to $5.03. The company's market cap stands at $52.7 million. </li>
</ul>
<h3>Losers</h3>
<ul>
<li>Elutia (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/ELUT#NASDAQ">ELUT</a>) shares fell 54.7% to $0.91 during Tuesday's pre-market session. The market value of their outstanding shares is at $37.1 million. </li>
<li>Geovax Labs (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/GOVX#NASDAQ">GOVX</a>) shares decreased by 29.92% to $0.75. The company's market cap stands at $7.0 million. </li>
<li>Spruce Biosciences (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/SPRB#NASDAQ">SPRB</a>) stock fell 23.35% to $0.24. The company's market cap stands at $9.9 million. </li>
<li>Nexalin Technology (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/NXL#NASDAQ">NXL</a>) stock fell 21.34% to $1.4. The market value of their outstanding shares is at $18.6 million. </li>
<li>Longevity Health Holdings (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/XAGE#NASDAQ">XAGE</a>) shares decreased by 21.03% to $0.16. The market value of their outstanding shares is at $4.8 million. </li>
<li>Sophia Genetics (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/SOPH#NASDAQ">SOPH</a>) stock decreased by 20.42% to $2.3. The company's market cap stands at $152.8 million. 
See Also: <a href="http://www.benzinga.com/money/best-healthcare-stocks/" title="www.benzinga.com/money/best-healthcare-stocks/">www.benzinga.com/money/best-healthcare-stocks/</a></li>
</ul>
This article was generated by Benzinga's automated content engine and reviewed by an editor.

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Longevity Health Holdings, Inc. - Common Stock

XAGE

12 Health Care Stocks Moving In Tuesday's Pre-Market Session

Biologics License Application (BLA) Submission to U.S. FDA for Tralesinidase Alfa Enzyme Replacement Therapy (TA-ERT) Anticipated in 1H 2026

Spruce Biosciences Secures Global Rights to TA-ERT, Aims For Accelerated FDA Approval In 2026

<h3>Gainers</h3>
<ul>
<li>Citius Oncology (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/CTOR#NASDAQ">CTOR</a>) stock moved upwards by 66.9% to $1.11 during Monday's pre-market session. The market value of their outstanding shares is at $79.4 million. </li>
<li>Corcept Therapeutics (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/CORT#NASDAQ">CORT</a>) shares rose 44.99% to $79.21. The market value of their outstanding shares is at $8.3 billion. </li>
<li>Spruce Biosciences (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/SPRB#NASDAQ">SPRB</a>) shares moved upwards by 18.6% to $0.35. The market value of their outstanding shares is at $14.4 million. </li>
<li>Apollomics (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/APLM#NASDAQ">APLM</a>) shares rose 17.73% to $8.96. The market value of their outstanding shares is at $9.8 million. </li>
<li>Know Labs (AMEX:<a class="ticker" href="https://www.benzinga.com/stock/KNW#AMEX">KNW</a>) shares moved upwards by 15.78% to $0.85. The market value of their outstanding shares is at $2.3 million. </li>
<li>Aprea Therapeutics (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/APRE#NASDAQ">APRE</a>) stock rose 15.31% to $2.41. The market value of their outstanding shares is at $13.0 million. The company's, Q4 earnings came out 4 days ago. </li>
</ul>
<h3>Losers</h3>
<ul>
<li>Vaxcyte (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/PCVX#NASDAQ">PCVX</a>) shares declined by 32.1% to $47.16 during Monday's pre-market session. The market value of their outstanding shares is at $6.0 billion. </li>
<li>PAVmed (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/PAVM#NASDAQ">PAVM</a>) shares decreased by 19.8% to $0.6. The market value of their outstanding shares is at $8.2 million. As per the press release, Q4 earnings came out 4 days ago. </li>
<li>LogicMark (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/LGMK#NASDAQ">LGMK</a>) stock declined by 19.69% to $0.02. </li>
<li>InnovAge Holding (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/INNV#NASDAQ">INNV</a>) shares fell 19.67% to $2.41. The market value of their outstanding shares is at $325.9 million. </li>
<li>Sharps Technology (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/STSS#NASDAQ">STSS</a>) stock declined by 18.92% to $0.03. </li>
<li>SANUWAVE Health (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/SNWV#NASDAQ">SNWV</a>) stock decreased by 17.93% to $30.0. The market value of their outstanding shares is at $256.4 million. 
See Also: <a href="http://www.benzinga.com/money/best-healthcare-stocks/" title="www.benzinga.com/money/best-healthcare-stocks/">www.benzinga.com/money/best-healthcare-stocks/</a></li>
</ul>
This article was generated by Benzinga's automated content engine and reviewed by an editor.

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Guggenheim analyst Evan Wang reiterates Spruce Biosciences (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/SPRB#NASDAQ">SPRB</a>) from Neutral to Neutral.

Guggenheim Reiterates Neutral on Spruce Biosciencesto Neutral

JMP Securities analyst Jonathan Wolleben downgrades Spruce Biosciences (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/SPRB#NASDAQ">SPRB</a>) from Market Outperform to Market Perform and maintains the price target from $3 to $3.

Downgrades

JMP Securities Downgrades Spruce Biosciences to Market Perform, Maintains Price Target to $3

Press Releases

Spruce Biosciences Presented Phase 2 POWER Study Results of Tildacerfont for the Treatment of Polycystic Ovary Syndrome at ENDO 2024

Spruce Biosciences and HMNC Brain Health Announce Strategic Collaboration to Develop Treatment for Major Depressive Disorder (MDD)

Spruce Biosciences Recognized as a Bay Area Best Place to Work

Spruce Biosciences Reports Second Quarter 2024 Financial Results and Provides Corporate Updates

Spruce Biosciences to Participate in the H.C. Wainwright 26th Annual Global Investment Conference

Spruce Biosciences to Participate in the Guggenheim Securities Healthcare Innovation Conference

Spruce Biosciences Reports Third Quarter 2024 Financial Results and Provides Corporate Updates

Spruce Biosciences Announces Topline Results from CAHmelia-204 in Adult CAH and CAHptain-205 in Adult and Pediatric CAH

Spruce Biosciences Announces New Corporate Strategy and Acquisition of Tralesinidase Alfa for the Treatment of Sanfilippo Syndrome Type B (MPS IIIB)

Spruce Biosciences Reports First Quarter 2025 Financial Results and Provides Corporate Updates

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