L'intérêt à découvert pour Sensei Biotherapeutics donne aux investisseurs une idée du degré auquel les investisseurs parient sur la baisse de l'action de Sensei Biotherapeutics. Les données sur l'intérêt à découvert sont mises à jour toutes les deux semaines.

Sensei Biotherapeutics (NASDAQ:SNSE) Stock, Rapport sur les intérêts à découvert

SENSEI BIOTHERAPEUTICS INC

Sensei Biotherapeutics

Sensei Biotherapeutics Inc is an immuno-oncology company focused on the discovery and development of next-generation therapeutics for cancer patients. Its TMAb (Tumor Microenvironment Activated Biologics) platform developing highly selective therapeutics designed to disable immunosuppressive signals or activate immunostimulatory signals selectively in the tumor microenvironment. The company have four investigational product candidates in various stages of development: SNS-101, SNS-102, SNS-103, SNS-20.

Sensei Biotherapeutics, Inc. - Common Stock

Sensei Biotherapeutics Inc

News

L3Harris Delivers First Missionized Skyraider II Aircraft To Support U.S. Air Force Special Operations Command

WF International Limited Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/WXM#NASDAQ">WXM</a>) shares are trading lower Thursday on <a href="https://www.benzinga.com/pressreleases/25/04/g44617931/wf-international-limited-announces-closing-of-initial-public-offering">continued IPO volatility</a>. 
What To Know: WF International announced the closing of its IPO of 1.4 million ordinary shares for $4 per share. 
The Chengdu-based company, which provides electromechanical solutions including HVAC and water purification systems, said it raised $5.6 million in gross proceeds from the IPO.
The company made its public debut on the Nasdaq Capital Market this week, but the stock has trended lower since. The sharp decline may suggest a lack of strong demand. It&#8217;s also worth noting that broader markets are facing heavy selling pressure Thursday following reciprocal tariffs from the Trump administration.
WF International said it granted the underwriters a 30-day option to purchase an additional 210,000 shares at the offering price. The Benchmark Company and Axiom Capital Management acted as joint book-running managers.
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WXM Price Action: WF International shares were down 24.1% at $2.17 at the time of publication, according to <a href="https://pro.benzinga.com/dashboard?new_user=False&amp;backend=google-oauth2'">Benzinga Pro.</a>
<figure class="wp-block-image size-large is-resized"><a href="https://www.benzinga.com/pro/register?utm_adType=bzprocontent&amp;utm_campaign=14daytrial&amp;utm_ad=0403"><img loading="lazy" decoding="async" width="1024" height="531" src="https://editorial-assets.benzinga.com/wp-content/uploads/2025/04/03140214/Screenshot-2025-04-03-at-14.01.53-1024x531.png" alt="" class="wp-image-856175" style="width:411px;height:auto" srcset="https://editorial-assets.benzinga.com/wp-content/uploads/2025/04/03140214/Screenshot-2025-04-03-at-14.01.53-1024x531.png 1024w,https://editorial-assets.benzinga.com/wp-content/uploads/2025/04/03140214/Screenshot-2025-04-03-at-14.01.53-300x156.png 300w,https://editorial-assets.benzinga.com/wp-content/uploads/2025/04/03140214/Screenshot-2025-04-03-at-14.01.53-768x398.png 768w,https://editorial-assets.benzinga.com/wp-content/uploads/2025/04/03140214/Screenshot-2025-04-03-at-14.01.53.png 1517w" sizes="(max-width: 1024px) 100vw, 1024px" /></a></figure>
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Movers

WF International Stock Continues To Fall: What's Going On?

Government

Macro Economic Events

Regulations

Politics

Economics

General

Asked If There Are Concerns That China Will Cut Off Supplies Of Pharmaceuticals, White House's Hassett Says Don't Think People Need To Be Worried About That

NBA Hall-of-Famer Earvin "Magic" Johnson is one of the rare athletes who can legitimately claim to be a better businessman than he was as a player. It may come as a surprise, but Johnson believes that thinking about helping other people was one of the keys to building his multi-billion-dollar business empire.
The<a href="https://247wallst.com/personal-finance/2025/03/10/magic-johnson-is-worth-billions-and-says-if-you-want-to-build-wealth-you-cant-just-think-about-your-own-pockets/"> 24/7 Wallstreet</a> website quoted an interview from 2008 where Johnson said, "It&#8217;s easier to build wealth if you think about others instead of only focusing on filling your own pockets." Although that advice sounds counterintuitive, Johnson's logic becomes clear when you look at his business career in its entirety. One of Magic's first and most public forays into the business came when his adopted hometown needed him more than ever.
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It was 1995, four years after Johnson had announced his first retirement from the NBA due to having contracted HIV. The South-Central community of Los Angeles was trying to rebuild after the devastation caused by the rioting that broke out after the Rodney King verdict. The riots, which did hundreds of millions of dollars in damage to the community, had essentially scared off the major private investors needed for a rebuild of that scale.
Johnson, who made an estimated $40 million during his playing career, had always dreamed of becoming a businessman. He also had a deep desire to help rebuild the community. In South Central, Johnson saw an opportunity. Johnson stepped into the fray by opening the Magic Johnson Crenshaw 15 movie theaters in the Baldwin Hills Mall on Crenshaw Boulevard in South Central.
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However, Johnson didn't open just any movie theater. He opened up a first-class operation that featured stadium-style seating, multiple concession stands, and state-of-the-art surround sound technology. Those features were commonplace in suburban theaters, but they were virtually absent in South L.A. or any of America's historically underserved communities.
It was a big risk, but it paid off brilliantly for Johnson. Soon, Johnson's chain expanded to Harlem and other minority communities nationwide. Their success was pivotal in convincing big-box stores and retailers like Old Navy that investing in minority neighborhoods could be just as profitable as opening in the suburbs. Johnson, who had a contact list full of top-tier business connections, wasn't done.
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In 1998, Johnson convinced Starbucks (NASDAQ:<a href="https://www.benzinga.com/quote/SBUX"> SBUX</a>) CEO Howard Schultz to let him open and operate multiple franchises in minority communities. Their first outlet opened on Crenshaw Boulevard in L.A., just a few blocks north of his theaters. According to the<a href="https://web.archive.org/web/20101020184051/https:/lakersblog.latimes.com/lakersblog/2010/10/magic-johnson-sells-his-starbucks-franchises.html"> Los Angeles Times</a>, Johnson eventually opened 125<a href="https://www.benzinga.com/insights/news/25/03/44377541/heres-how-much-1000-invested-in-starbucks-20-years-ago-would-be-worth-today"> Starbucks</a> outlets nationwide before selling 105 of them back to Starbucks for $100 million.&nbsp;
Johnson's investments and business deals are run through his company, Magic Johnson Enterprises, which he founded in 1987. Today, it's a multibillion-dollar operation with ownership stakes&nbsp; in the Los Angeles Dodgers and the NFL's Washington Commanders. Much of Johnson's early business success was built on his willingness to help himself by helping others.
Could incorporating Johnson's ethos into your<a href="https://www.benzinga.com/personal-finance/25/03/44440238/can-you-guess-how-much-you-need-to-build-generational-wealth-some-say-its-less-than-what-it-takes-to-feel-rich"> wealth-building strategy</a> yield similar results? You may not want to help rebuild an entire community, but having a larger sense of purpose can sharpen your focus. You can find your motivation anywhere. Once you do, working toward your goal will become a labor of love.
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Personal Finance

Magic Johnson Is Worth Billions—But He Says You Can't Get There Thinking Only About Yourself

HubSpot's (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/HUBS#NYSE">HUBS</a>) short percent of float has risen 35.62% since its last report. The company recently reported that it has 991 thousand shares sold short, which is 1.98% of all regular shares that are available for trading. Based on its trading volume, it would take traders 1.18 days to cover their short positions on average.
<h3>Why Short Interest Matters</h3>
Short interest is the number of shares that have been sold short but have not yet been covered or closed out. <a href="https://www.benzinga.com/money/how-to-short-a-stock?adType=benzinga-insights&amp;ad=short-interest&amp;campaign=wallstreetadvantage">Short selling</a> is when a trader sells shares of a company they do not own, with the hope that the price will fall. Traders make money from short selling if the price of the stock falls and they lose if it rises.
Short interest is important to track because it can act as an indicator of market sentiment towards a particular stock. An increase in short interest can signal that investors have become more bearish, while a decrease in short interest can signal they have become more bullish.
See Also: <a href="https://www.benzinga.com/short-interest?adType=benzinga-insights&amp;ad=short-interest&amp;campaign=wallstreetadvantage">List of the most shorted stocks</a>
<h3>HubSpot Short Interest Graph (3 Months)</h3>
<img src="https://www.benzinga.com/files/images/story/2025/1743708628_0.png" alt="short_fig" />
As you can see from the chart above the percentage of shares that are sold short for HubSpot has grown since its last report. This does not mean that the stock is going to fall in the near-term but traders should be aware that more shares are being shorted.
<h3>Comparing HubSpot's Short Interest Against Its Peers</h3>
Peer comparison is a popular technique amongst analysts and investors for gauging how well a company is performing. A company's peer is another company that has similar characteristics to it, such as industry, size, age, and financial structure. You can find a company's peer group by reading its 10-K, proxy filing, or by doing your own similarity analysis.
According to <a href="https://www.benzinga.com/pro/">Benzinga Pro</a>, HubSpot's peer group average for short interest as a percentage of float is 3.11%, which means the company has less short interest than most of its peers.
Did you know that increasing short interest can actually be bullish for a stock? <a href="https://www.benzinga.com/money/how-to-make-money-on-a-short-squeeze?adType=benzinga-insights&amp;ad=short-interest&amp;campaign=wallstreetadvantage">This post by Benzinga Money explains how you can profit from it.</a>
This article was generated by Benzinga's automated content engine and was reviewed by an editor.

Short Sellers

Short Ideas

Trading Ideas

HUBS

Peering Into HubSpot's Recent Short Interest

IES Hldgs's (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/IESC#NYSE">IESC</a>) short percent of float has fallen 3.42% since its last report. The company recently reported that it has 649 thousand shares sold short, which is 7.34% of all regular shares that are available for trading. Based on its trading volume, it would take traders 2.54 days to cover their short positions on average.
<h3>Why Short Interest Matters</h3>
Short interest is the number of shares that have been sold short but have not yet been covered or closed out. <a href="https://www.benzinga.com/money/how-to-short-a-stock?adType=benzinga-insights&amp;ad=short-interest&amp;campaign=wallstreetadvantage">Short selling</a> is when a trader sells shares of a company they do not own, with the hope that the price will fall. Traders make money from short selling if the price of the stock falls and they lose if it rises.
Short interest is important to track because it can act as an indicator of market sentiment towards a particular stock. An increase in short interest can signal that investors have become more bearish, while a decrease in short interest can signal they have become more bullish.
See Also: <a href="https://www.benzinga.com/short-interest?adType=benzinga-insights&amp;ad=short-interest&amp;campaign=wallstreetadvantage">List of the most shorted stocks</a>
<h3>IES Hldgs Short Interest Graph (3 Months)</h3>
<img src="https://www.benzinga.com/files/images/story/2025/1743708624_0.png" alt="short_fig" />
As you can see from the chart above the percentage of shares that are sold short for IES Hldgs has declined since its last report. This does not mean that the stock is going to rise in the near-term but traders should be aware that less shares are being shorted.
<h3>Comparing IES Hldgs's Short Interest Against Its Peers</h3>
Peer comparison is a popular technique amongst analysts and investors for gauging how well a company is performing. A company's peer is another company that has similar characteristics to it, such as industry, size, age, and financial structure. You can find a company's peer group by reading its 10-K, proxy filing, or by doing your own similarity analysis.
According to <a href="https://www.benzinga.com/pro/">Benzinga Pro</a>, IES Hldgs's peer group average for short interest as a percentage of float is 5.74%, which means the company has more short interest than most of its peers.
Did you know that increasing short interest can actually be bullish for a stock? <a href="https://www.benzinga.com/money/how-to-make-money-on-a-short-squeeze?adType=benzinga-insights&amp;ad=short-interest&amp;campaign=wallstreetadvantage">This post by Benzinga Money explains how you can profit from it.</a>
This article was generated by Benzinga's automated content engine and was reviewed by an editor.

IESC

Is IES Hldgs Gaining or Losing Market Support?

Archrock's (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/AROC#NYSE">AROC</a>) short percent of float has fallen 24.41% since its last report. The company recently reported that it has 5.53 million shares sold short, which is 3.22% of all regular shares that are available for trading. Based on its trading volume, it would take traders 3.06 days to cover their short positions on average.
<h3>Why Short Interest Matters</h3>
Short interest is the number of shares that have been sold short but have not yet been covered or closed out. <a href="https://www.benzinga.com/money/how-to-short-a-stock?adType=benzinga-insights&amp;ad=short-interest&amp;campaign=wallstreetadvantage">Short selling</a> is when a trader sells shares of a company they do not own, with the hope that the price will fall. Traders make money from short selling if the price of the stock falls and they lose if it rises.
Short interest is important to track because it can act as an indicator of market sentiment towards a particular stock. An increase in short interest can signal that investors have become more bearish, while a decrease in short interest can signal they have become more bullish.
See Also: <a href="https://www.benzinga.com/short-interest?adType=benzinga-insights&amp;ad=short-interest&amp;campaign=wallstreetadvantage">List of the most shorted stocks</a>
<h3>Archrock Short Interest Graph (3 Months)</h3>
<img src="https://www.benzinga.com/files/images/story/2025/1743708618_0.png" alt="short_fig" />
As you can see from the chart above the percentage of shares that are sold short for Archrock has declined since its last report. This does not mean that the stock is going to rise in the near-term but traders should be aware that less shares are being shorted.
<h3>Comparing Archrock's Short Interest Against Its Peers</h3>
Peer comparison is a popular technique amongst analysts and investors for gauging how well a company is performing. A company's peer is another company that has similar characteristics to it, such as industry, size, age, and financial structure. You can find a company's peer group by reading its 10-K, proxy filing, or by doing your own similarity analysis.
According to <a href="https://www.benzinga.com/pro/">Benzinga Pro</a>, Archrock's peer group average for short interest as a percentage of float is 8.40%, which means the company has less short interest than most of its peers.
Did you know that increasing short interest can actually be bullish for a stock? <a href="https://www.benzinga.com/money/how-to-make-money-on-a-short-squeeze?adType=benzinga-insights&amp;ad=short-interest&amp;campaign=wallstreetadvantage">This post by Benzinga Money explains how you can profit from it.</a>
This article was generated by Benzinga's automated content engine and was reviewed by an editor.

AROC

What's Driving the Market Sentiment Around Archrock?

On Thursday, Goldman Sachs analyst Brooke Roach discussed the impact of the U.S. reciprocal tariffs on retail companies.
On April 2, President Trump announced reciprocal tariffs, including a 10% hike on all countries except Mexico and Canada, with higher rates for select nations with trade deficits.
The most significant retail impact is expected from increased tariffs on major sourcing partners like Vietnam, Indonesia, Bangladesh, and Cambodia, said the analyst.
The U.S. is significantly raising tariffs on imports, with China&#8217;s tariff rate increasing to 54% (up from 20%). Other key sourcing countries like Vietnam (46%), Indonesia (32%), Bangladesh (37%), Cambodia (49%), and India (27%) will also see tariff hikes, while EU imports face a 20% tariff.
Canada and Mexico remain exempt under USMCA, though non-USMCA compliant goods will be taxed at 12%. Overall, apparel and footwear tariffs are estimated to rise to an average of 38%, noted the analyst.
Additionally, the de minimis duty-free exemption for packages under $800 from China and Hong Kong will end on May 1, 2025.
These shipments will face a 30% tariff or $25 per item, increasing to $50 per item after June 1, 2025. The Secretary of Commerce will review within 90 days whether to expand this policy to Macau.
The newly announced tariffs will pressure brands and retailers, forcing them to adjust pricing, negotiate with vendors, and optimize costs to protect margins.
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While most companies will be affected, some are less exposed, including brands with lower U.S. sales exposure like Amer Sports Inc (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/AS#NYSE">AS</a>), Canada Goose Holdings Inc (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/GOOS#NYSE">GOOS</a>) and PVH Corp (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/PVH#NYSE">PVH</a>). Retailers with indirect sourcing, such as department stores and off-price retailers, could benefit from supply chain disruptions.
Companies that do not source their product from international markets or source from exempt regions, such as Savers Value Village Inc&#8217;s (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/SVV#NYSE">SVV</a>) with thrift business model and Kontoor Brands Inc&#8217;s (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/KTB#NYSE">KTB</a>) reliance on Mexico, though it also sources from Bangladesh, are less exposed.
The analyst notes that brands with momentum and strong consumer engagement are likely to have more substantial relative pricing power in the marketplace overall.
The analyst noted higher exposure to incrementally new tariffs from Vietnam and Cambodia-exposed businesses include sportswear like Lululemon Athletica Inc (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/LULU#NASDAQ">LULU</a>), Nike Inc (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/NKE#NYSE">NKE</a>) and general apparel like Torrid Holdings Inc (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/CURV#NYSE">CURV</a>), Figs Inc (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/FIGS#NYSE">FIGS</a>), Victoria&#8217;s Secret &amp; Co (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/VSCO#NYSE">VSCO</a>), and Gap Inc (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/GAP#NYSE">GAP</a>).
The Home Furnishings industry with companies like RH (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/RH#NYSE">RH</a>) and Williams-Sonoma Inc (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/WSM#NYSE">WSM</a>) faces the greatest risk from tariffs due to its high exposure to China and Vietnam and the discretionary nature of its products.
RH sources 72% of its products from Asia, including 23% from China and 35% from Vietnam, while WSM has 23% China and 14% Vietnam exposure.
Retailers Five Below Inc (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/FIVE#NASDAQ">FIVE</a>) and Best Buy Co Inc (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/BBY#NYSE">BBY</a>) are also vulnerable, with 60% of their products sourced from China. While Vietnam exposure remains unclear for most industries, home furnishing companies have the highest risk, said the analyst.
On the other hand, Auto Parts companies like Advance Auto Parts Inc (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/AAP#NYSE">AAP</a>), AutoZone Inc (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/AZO#NYSE">AZO</a>) and O&#8217;Reilly Automotive Inc (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/ORLY#NASDAQ">ORLY</a>) and Home Improvement retailers like Home Depot Inc (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/HD#NYSE">HD</a>) and Lowe&#8217;s Companies Inc (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/LOW#NYSE">LOW</a>) are better positioned, as they can pass increased costs.
Similarly, retailers that sell food like Walmart Inc (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/WMT#NYSE">WMT</a>), BJ&#8217;s Wholesale Club Holdings Inc (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/BJ#NYSE">BJ</a>), and Costco Wholesale Corp (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/COST#NASDAQ">COST</a>) are relatively insulated.
Companies with minimal reliance on China, such as Ulta Beauty Inc (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/ULTA#NASDAQ">ULTA</a>) and Bath &amp; Body Works Inc (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/BBWI#NYSE">BBWI</a>), are also well-positioned against these tariffs.
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Image via Shutterstock.

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BBWI

COST

CURV

FIGS

FIVE

GOOS

LULU

ORLY

ULTA

VSCO

Goldman Sachs Warns Tariffs Will Hit Apparel And Home Furnishings Hardest, Highlights Most Exposed Stocks

Guidance

STLA

Stellantis Says Because Of Engine Shortage, Company Will Idle Warren, Michigan Truck Assembly Plant For Several Weeks Starting April 14

Several restaurant stocks are taking a beating on Thursday as broader markets tumble in reaction to sweeping reciprocal tariffs from <a href="https://www.benzinga.com/news/global/25/04/44632479/retail-stocks-slammed-as-trumps-tariff-plan-sends-shockwaves-through-sector">the Trump administration</a>.
What Happened: President Donald Trump announced new tariffs on several countries across the world on Wednesday, sending markets into a tailspin.
Restaurant stocks are getting hit particularly hard as restaurant chains typically source food machinery and packaging from China. Trump announced 34% tariffs on China this week. 
According to a Wall Street Journal <a href="https://www.wsj.com/livecoverage/trump-tariffs-trade-war-stock-market-04-03-2025/card/restaurant-stocks-slide-on-trump-s-new-duties-IrOe9ndIoLz9heJhUlgk">report</a>, many restaurant chains buy potatoes from Canada and often import meats from other countries. 
Starbucks Corp (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/SBUX#NASDAQ">SBUX</a>) has significant exposure to China as the company operates thousands of stores in the country. Starbucks had a total of 7,685 stores in China as of the end of 2024. The company is also a big coffee importer. Shares were down more than 11% at last check, per <a href="http://pro.benzinga.com">Benzinga Pro</a>.
Chipotle Mexican Grill Inc (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/CMG#NYSE">CMG</a>) is also facing selling pressure as the company imports avocados from Mexico, Columbia and other countries globally. Chipotle shares were down about 3.5% at the time of writing.
Here&#8217;s a look at some other restaurant stocks moving lower Thursday:
<ul>
<li>Dutch Bros Inc (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/BROS#NYSE">BROS</a>) down 9.05% at $56.24</li>
</ul>
<ul>
<li>Shake Shack Inc (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/SHAK#NYSE">SHAK</a>) down 11.7% at $83.69</li>
</ul>
<ul>
<li>CAVA Group Inc (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/CAVA#NYSE">CAVA</a>) down 7.49% at $83.01</li>
</ul>
<ul>
<li>Bloomin&#8217; Brands Inc (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/BLMN#NASDAQ">BLMN</a>) down 8.25% at $7.15</li>
</ul>
<ul>
<li>Cracker Barrel Old Country Store Inc (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/CBRL#NASDAQ">CBRL</a>) down 13.5% at $35.48</li>
</ul>
<ul>
<li>Portillo&#8217;s Inc (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/PTLO#NASDAQ">PTLO</a>) down 8.24% at $11.50</li>
</ul>
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Photo: Shutterstock.

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Restaurant Stocks Are Getting Cooked Thursday As Trump Tariffs Rattle Markets

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Shares of homebuilders and housing-linked stocks are trading lower as markets react to President Trump's announcement of sweeping tariffs.

In March,&nbsp;Sarepta Therapeutics, Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/SRPT#NASDAQ">SRPT</a>) shared an update on Elevidys (delandistrogene moxeparvovec-rokl), the only approved gene therapy in patients with Duchenne muscular dystrophy.
The company reported a patient death following treatment with Elevidys, having suffered <a target="_blank" href="https://www.benzinga.com/25/03/44376919/sarepta-therapeutics-reports-patient-death-post-elevidys-gene-therapy-treatment-stock-plunges" rel="noreferrer noopener">acute liver failure</a>.
Acute liver injury is a known possible side effect of Elevidys and other AAV-mediated gene therapies and is highlighted in the prescribing information.
On Wednesday, Sarepta and Roche Holdings AG (OTC:<a class="ticker" href="https://www.benzinga.com/stock/RHHBY#OTC">RHHBY</a>) temporarily <a target="_blank" href="https://www.duchenneuk.org/roche-temporarily-halts-clinic-studies/" rel="noreferrer noopener">halted</a> several clinical studies.
Also Read: <a target="_blank" href="https://www.benzinga.com/general/biotech/25/01/43232532/sarepta-therapeutics-duchenne-gene-therapy-shows-sustained-benefits-and-disease-stabilization-at-two-years" rel="noreferrer noopener">Sarepta Therapeutics&#8217; Duchenne Gene Therapy Shows Sustained Benefits And Disease Stabilization At Two Years</a>
Roche, the company to which the treatment is licensed outside the US, has said that this was at the European Medicines Agency&#8217;s (EMA) request.
The companies have a therapeutic clinical hold on Study 104, Study 302, and Study 303 in the EU until the analysis of the cause of death is complete.
Roche is also pausing the enrollment and dosing of participants in the U.K. for its ENVOL study.
Patient safety monitoring for already enrolled participants and ongoing collection of data will continue.
In June 2024, the EMA validated and <a target="_blank" href="https://www.roche.com/investors/updates/inv-update-2024-06-24" rel="noreferrer noopener">initiated</a> a review of the marketing authorization application for Elevidys, a gene therapy for ambulatory patients aged 3-7 years old with Duchenne muscular dystrophy.
HC Wainwright upgraded Sarepta on Wednesday from Sell to Neutral, saying it is trading within a fair range.
Analyst Mitchell S. Kapoor still anticipates Elevidys revenue will fall short in the second half of 2025—especially after the recent patient death due to acute liver injury.
Kapoor sees a risk that Elevidys sales may decline faster than expected, possibly as early as Q2 2025, due to growing hesitation from doctors and patients regarding its safety. The treatment&#8217;s limited effectiveness heightens this concern.
The analyst maintains the price <a target="_blank" href="https://www.benzinga.com/quote/SRPT/analyst-ratings" rel="noreferrer noopener">forecast of $75 per share</a>.
Needham maintained Sarepta Therapeutics with a Buy, lowering the price forecast from $202 to $183.
Price Action: SRPT stock is down 6.68% at $58.30 at the last check Thursday.
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Image via Sarepta Therapeutics

Biotech

Large Cap

RHHBY

SRPT

Sarepta/Roche Suspend Elevidys Gene Therapy Trials In Europe After Patient Death

Goldman Sachs analyst Alexander Blostein expects macro and policy uncertainty, volatile equity markets, and declining short-term interest rates to weigh on EPS <a target="_blank" href="https://www.benzinga.com/topic/bank" rel="noreferrer noopener">forecasts for Capital Markets stocks</a>.
The analyst&#8217;s 2025 estimates are ~5% below consensus on average, except for Exchanges.
Blostein says Alternative Manager stocks face heightened EPS risks due to weaker realization activity (potential 30% downside to Street estimates) and a slower FRE growth trajectory, now expected to average 11% in 2025E,<a target="_blank" href="https://www.benzinga.com/quote/tpg/analyst-ratings" rel="noreferrer noopener"> down from ~15% previously</a>.
The analyst writes that Brookfield Asset Management Inc (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/BAM#NYSE">BAM</a>) appears among the most resilient, <a target="_blank" href="https://www.benzinga.com/quote/bam/analyst-ratings" rel="noreferrer noopener">benefiting from index inclusion</a>.
While TPG Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/TPG#NASDAQ">TPG</a>) and KKR &amp; Co. Inc. (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/KKR#NYSE">KKR</a>) offer attractive valuations, further EPS estimate revisions may be <a target="_blank" href="https://www.benzinga.com/quote/kkr/analyst-ratings" rel="noreferrer noopener">necessary, adds the analyst</a>.
On the other hand, the analyst says that the Brokers and Wealth Advisor stocks face an average 4%<a target="_blank" href="https://www.benzinga.com/quote/schw/analyst-ratings" rel="noreferrer noopener"> downside to 2025/2026 EPS estimates</a>.
Charles Schwab Corporation (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/SCHW#NYSE">SCHW</a>) is performing better (+5% first-quarter EPS beat), while Stifel Financial Corporation (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/SF#NYSE">SF</a>) is lagging <a target="_blank" href="https://www.benzinga.com/quote/sf/analyst-ratings" rel="noreferrer noopener">(-10% EPS miss), adds the analyst</a>.
Blostein expects lower short-term interest rates, weaker equity markets, and slower Investment Banking activity in 2025 to weigh on EPS, though he anticipates higher cash balances in March and stronger retail engagement to provide some relief.
Meanwhile, the analyst projects Traditional Managers to face ~5% EPS downside in 2025/26, with T. Rowe Price Group, Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/TROW#NASDAQ">TROW</a>) and Janus Henderson Group plc (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/JHG#NYSE">JHG</a>) facing high-single-digits <a target="_blank" href="https://www.benzinga.com/quote/jhg/analyst-ratings" rel="noreferrer noopener">EPS risks in 2025/26.</a>
Blostein expects long-term average AUM to decline ~1% q/q, with <a target="_blank" href="https://www.benzinga.com/quote/trow/analyst-ratings" rel="noreferrer noopener">weaker second-quarter momentum</a>.
Fixed Income and Active ETFs show strength, but Active Equities outflows may drive a -2.0% annualized organic decline, adds the analyst.
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Image via Shutterstock.

Mid Cap

Janus Henderson Group plc Ordinary Shares

SCHW

TROW

Goldman Sachs Sees Broad EPS Pressure Across Capital Markets, Highlights Brookfield As A Standout

Researchers investigated whether the shingles (herpes zoster) vaccine can help prevent dementia. Previous studies suggest that certain herpes viruses may contribute to dementia, and vaccines might have <a target="_blank" href="https://www.benzinga.com/general/health-care" rel="noreferrer noopener">immune benefits</a>.
The new research, published on Wednesday, Nature analyzed data from 282,541 older adults in Wales and found that people who received the original shingles live virus vaccine were 20% less likely to develop dementia than non-vaccinated participants.
Also Read: <a target="_blank" href="https://www.benzinga.com/general/biotech/25/03/44395415/trump-administration-weighs-deep-cuts-to-domestic-hiv-prevention-programs-gilead-stock-slides" rel="noreferrer noopener">Trump Administration Weighs Deep Cuts To Domestic HIV Prevention Programs, Gilead Stock Slides</a>
Shingles, also known as herpes zoster, is&nbsp;a painful rash illness caused by the varicella-zoster virus, the same virus that causes chickenpox, which reactivates in the body after a person has had chickenpox.
The <a target="_blank" href="https://www.nature.com/articles/s41586-025-08800-x#Sec4" rel="noreferrer noopener">study</a> found that getting the zoster vaccine lowered the chance of being diagnosed with dementia over seven years by 3.5 percentage points, or about 20% relative risk reduction.
The protective effect was stronger in women than men. The findings were confirmed in another population (England and Wales) using death certificate data, showing fewer dementia-related deaths among vaccinated individuals.
Previous research in July 2024 <a target="_blank" href="https://www.nature.com/articles/s41591-024-03201-5" rel="noreferrer noopener">hinted</a> that the older live shingles vaccine might offer some protection, but that vaccine has been discontinued in favor of the recombinant version.
Researchers found that people who received the recombinant vaccine had a 17% longer period without a dementia diagnosis—equal to about 164 extra days dementia-free for those who eventually developed the condition.
The recombinant vaccine also appeared to reduce dementia risk more than flu and tetanus–diphtheria–pertussis vaccines. The effect was seen in both men and women but was stronger in women.
Last year, GSK plc (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/GSK#NYSE">GSK</a>) revealed data from the ZOSTER-049 long-term follow-up phase 3 trial, which followed participants for up to approximately 11 years following initial vaccination with Shingrix <a target="_blank" href="https://www.benzinga.com/general/biotech/24/04/38289827/gsk-says-its-blockbuster-shingles-vaccine-shows-high-efficacy-even-after-10-years" rel="noreferrer noopener">(Recombinant Zoster Vaccine or RZV)</a>.&nbsp;
The final trial data demonstrate that RZV has maintained efficacy against shingles in adults over 50 for over a decade.&nbsp;
Shingrix sales for 2024 reached 3.36 billion pounds, down 2% (+1% at <a target="_blank" href="https://www.benzinga.com/25/02/43492835/gsk-launches-share-buyback-of-around-25-billion-after-better-than-expected-q4-earnings-raises-long-term-annual-sales-forecast-to-over-50-billion" rel="noreferrer noopener">constant currency)</a>.
Price Action: GSK stock is up 3.71% at $39.04 at the last check Thursday.
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Photo by HJBC via Shutterstock

Health Care

New Study Shows Shingles Vaccine Linked To 20% Lower Dementia Risk, GSK Stock Pops

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Shares of construction-related stocks are trading lower as markets react to President Trump's announcement of sweeping tariffs.

Molina Healthcare's (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/MOH#NYSE">MOH</a>) short percent of float has risen 16.85% since its last report. The company recently reported that it has 1.75 million shares sold short, which is 4.16% of all regular shares that are available for trading. Based on its trading volume, it would take traders 2.03 days to cover their short positions on average.
<h3>Why Short Interest Matters</h3>
Short interest is the number of shares that have been sold short but have not yet been covered or closed out. <a href="https://www.benzinga.com/money/how-to-short-a-stock?adType=benzinga-insights&amp;ad=short-interest&amp;campaign=wallstreetadvantage">Short selling</a> is when a trader sells shares of a company they do not own, with the hope that the price will fall. Traders make money from short selling if the price of the stock falls and they lose if it rises.
Short interest is important to track because it can act as an indicator of market sentiment towards a particular stock. An increase in short interest can signal that investors have become more bearish, while a decrease in short interest can signal they have become more bullish.
See Also: <a href="https://www.benzinga.com/short-interest?adType=benzinga-insights&amp;ad=short-interest&amp;campaign=wallstreetadvantage">List of the most shorted stocks</a>
<h3>Molina Healthcare Short Interest Graph (3 Months)</h3>
<img src="https://www.benzinga.com/files/images/story/2025/1743707727_0.png" alt="short_fig" />
As you can see from the chart above the percentage of shares that are sold short for Molina Healthcare has grown since its last report. This does not mean that the stock is going to fall in the near-term but traders should be aware that more shares are being shorted.
<h3>Comparing Molina Healthcare's Short Interest Against Its Peers</h3>
Peer comparison is a popular technique amongst analysts and investors for gauging how well a company is performing. A company's peer is another company that has similar characteristics to it, such as industry, size, age, and financial structure. You can find a company's peer group by reading its 10-K, proxy filing, or by doing your own similarity analysis.
According to <a href="https://www.benzinga.com/pro/">Benzinga Pro</a>, Molina Healthcare's peer group average for short interest as a percentage of float is 4.79%, which means the company has less short interest than most of its peers.
Did you know that increasing short interest can actually be bullish for a stock? <a href="https://www.benzinga.com/money/how-to-make-money-on-a-short-squeeze?adType=benzinga-insights&amp;ad=short-interest&amp;campaign=wallstreetadvantage">This post by Benzinga Money explains how you can profit from it.</a>
This article was generated by Benzinga's automated content engine and was reviewed by an editor.

Is the Market Bullish or Bearish on Molina Healthcare?

Digital Realty Trust's (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/DLR#NYSE">DLR</a>) short percent of float has risen 5.9% since its last report. The company recently reported that it has 8.28 million shares sold short, which is 3.23% of all regular shares that are available for trading. Based on its trading volume, it would take traders 3.09 days to cover their short positions on average.
<h3>Why Short Interest Matters</h3>
Short interest is the number of shares that have been sold short but have not yet been covered or closed out. <a href="https://www.benzinga.com/money/how-to-short-a-stock?adType=benzinga-insights&amp;ad=short-interest&amp;campaign=wallstreetadvantage">Short selling</a> is when a trader sells shares of a company they do not own, with the hope that the price will fall. Traders make money from short selling if the price of the stock falls and they lose if it rises.
Short interest is important to track because it can act as an indicator of market sentiment towards a particular stock. An increase in short interest can signal that investors have become more bearish, while a decrease in short interest can signal they have become more bullish.
See Also: <a href="https://www.benzinga.com/short-interest?adType=benzinga-insights&amp;ad=short-interest&amp;campaign=wallstreetadvantage">List of the most shorted stocks</a>
<h3>Digital Realty Trust Short Interest Graph (3 Months)</h3>
<img src="https://www.benzinga.com/files/images/story/2025/1743707722_0.png" alt="short_fig" />
As you can see from the chart above the percentage of shares that are sold short for Digital Realty Trust has grown since its last report. This does not mean that the stock is going to fall in the near-term but traders should be aware that more shares are being shorted.
<h3>Comparing Digital Realty Trust's Short Interest Against Its Peers</h3>
Peer comparison is a popular technique amongst analysts and investors for gauging how well a company is performing. A company's peer is another company that has similar characteristics to it, such as industry, size, age, and financial structure. You can find a company's peer group by reading its 10-K, proxy filing, or by doing your own similarity analysis.
According to <a href="https://www.benzinga.com/pro/">Benzinga Pro</a>, Digital Realty Trust's peer group average for short interest as a percentage of float is 4.93%, which means the company has less short interest than most of its peers.
Did you know that increasing short interest can actually be bullish for a stock? <a href="https://www.benzinga.com/money/how-to-make-money-on-a-short-squeeze?adType=benzinga-insights&amp;ad=short-interest&amp;campaign=wallstreetadvantage">This post by Benzinga Money explains how you can profit from it.</a>
This article was generated by Benzinga's automated content engine and was reviewed by an editor.

What Does the Market Think About Digital Realty Trust?

Advanced Energy Indus's (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/AEIS#NYSE">AEIS</a>) short percent of float has risen 13.15% since its last report. The company recently reported that it has 2.50 million shares sold short, which is 11.1% of all regular shares that are available for trading. Based on its trading volume, it would take traders 7.49 days to cover their short positions on average.
<h3>Why Short Interest Matters</h3>
Short interest is the number of shares that have been sold short but have not yet been covered or closed out. <a href="https://www.benzinga.com/money/how-to-short-a-stock?adType=benzinga-insights&amp;ad=short-interest&amp;campaign=wallstreetadvantage">Short selling</a> is when a trader sells shares of a company they do not own, with the hope that the price will fall. Traders make money from short selling if the price of the stock falls and they lose if it rises.
Short interest is important to track because it can act as an indicator of market sentiment towards a particular stock. An increase in short interest can signal that investors have become more bearish, while a decrease in short interest can signal they have become more bullish.
See Also: <a href="https://www.benzinga.com/short-interest?adType=benzinga-insights&amp;ad=short-interest&amp;campaign=wallstreetadvantage">List of the most shorted stocks</a>
<h3>Advanced Energy Indus Short Interest Graph (3 Months)</h3>
<img src="https://www.benzinga.com/files/images/story/2025/1743707717_0.png" alt="short_fig" />
As you can see from the chart above the percentage of shares that are sold short for Advanced Energy Indus has grown since its last report. This does not mean that the stock is going to fall in the near-term but traders should be aware that more shares are being shorted.
<h3>Comparing Advanced Energy Indus's Short Interest Against Its Peers</h3>
Peer comparison is a popular technique amongst analysts and investors for gauging how well a company is performing. A company's peer is another company that has similar characteristics to it, such as industry, size, age, and financial structure. You can find a company's peer group by reading its 10-K, proxy filing, or by doing your own similarity analysis.
According to <a href="https://www.benzinga.com/pro/">Benzinga Pro</a>, Advanced Energy Indus's peer group average for short interest as a percentage of float is 6.95%, which means the company has more short interest than most of its peers.
Did you know that increasing short interest can actually be bullish for a stock? <a href="https://www.benzinga.com/money/how-to-make-money-on-a-short-squeeze?adType=benzinga-insights&amp;ad=short-interest&amp;campaign=wallstreetadvantage">This post by Benzinga Money explains how you can profit from it.</a>
This article was generated by Benzinga's automated content engine and was reviewed by an editor.

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Press Releases

Sensei Biotherapeutics to Present at Upcoming Conferences

Sensei Biotherapeutics to Present Preclinical Data on SNS-103 at the CRI-ENCI Eighth International Immunotherapy Conference

Sensei Biotherapeutics to Present at Two Upcoming Scientific Conferences

Earnings

Sensei Biotherapeutics Reports Third Quarter 2024 Financial Results and Recent Business Highlights

Sensei Biotherapeutics to Participate in Citi's 2024 Global Healthcare Conference

Sensei Biotherapeutics Provides Corporate Update and Highlights Key Upcoming Milestones

Sensei Biotherapeutics to Participate in Oppenheimer's 35th Annual Healthcare Life Sciences Conference

Sensei Biotherapeutics Reports Favorable Preliminary Dose Expansion Data for Solnerstotug in PD-(L)1 Resistant Tumors

Sensei Biotherapeutics Reports Full Year 2024 Financial Results and Update on Clinical Progress

Sensei Biotherapeutics to Participate in the Canaccord Genuity Horizons in Oncology Virtual Conference

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