Dernières nouvelles pour Equillium (NASDAQ:EQ) Stock

Equillium

Equillium Inc is a clinical-stage biotechnology company engaged in developing novel therapeutics to treat severe autoimmune and inflammatory, or immuno-inflammatory, disorders with high unmet medical need. The company intends to commercialize its product candidates either independently or through partnerships, or otherwise monetize its pipeline through strategic transactions. Itolizumab (EQ001), a clinical-stage product candidate, is an anti-CD6 immune-modifying monoclonal antibody, or mAb, that selectively targets the CD6-ALCAM signaling pathway to downregulate pathogenic T effector cells while preserving T regulatory cells critical for maintaining a balanced immune response. The company's other clinical-stage and pre-clinical-stage candidates include EQ101 and EQ302.

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Analysts from Goldman Sachs have warned that the U.S. tariffs on Chinese imports could put up to 16 million jobs in China at risk, particularly in the manufacturing sector.
What Happened: The bank stated that persistently high U.S.-China tariffs and a significant drop in Chinese exports could put pressure on labor markets. The jobs under threat are primarily involved in the production of exports to the U.S., with nearly a quarter in the wholesale and retail sectors, <a href="https://www.scmp.com/economy/china-economy/article/3308140/us-tariffs-could-endanger-16-million-export-jobs-china-goldman-sachs">reported</a> the South China Morning Post.
"If high US-China tariffs were to persist and Chinese exports were to fall precipitously, labor markets would surely feel the pressure," stated the report
This year, the U.S. has levied tariffs of 145% on Chinese imports, pushing the effective tariff rate to around 156%. In retaliation, Beijing has imposed a 125% tariff on all U.S. goods, in addition to previous duties.
Goldman Sachs highlighted that communication equipment, apparel, and chemical products are more susceptible due to their significant share in US-bound exports from China. The bank also proposed that Chinese manufacturers could relocate production to third countries to circumvent high duties.
The report also noted that the U.S. removal of tariff exemptions for low-value package shipments is putting &#8217;employment pressure&#8217; on China's retail and wholesale sectors.
SEE ALSO:&nbsp;<a href="https://benzinga.com/trading-ideas/movers/25/04/45011721/intel-just-announced-q2-guidance-below-estimates-why-the-stock-is-tumbling" target="_blank" rel="noreferrer noopener">Intel Just Announced Q2 Guidance Below Estimates: Why The Stock Is Tumbling</a>
Why It Matters: Earlier this month,&nbsp;<a href="https://www.benzinga.com/government/regulations/25/04/44740040/chinas-growth-outlook-dims-as-trumps-125-tariffs-put-millions-of-jobs-at-risk-goldman-warns">Goldman Sachs warned</a>&nbsp;about a sluggish economic recovery for China and deep labor market consequences. As per the bank, the tariffs could reduce Chinese real GDP by 2.6 percentage points — with a 2.2 percentage point impact hitting as soon as 2025.
The bank also predicted that the possibility of a U.S.-China decoupling could lead to a massive<a href="https://www.benzinga.com/25/04/44787496/goldman-sachs-warns-25-trillion-sell-off-in-the-extreme-event-of-us-china-decoupling-as-scott-bessent-says-everything-is-on-the-table"> $2.5 trillion </a>sell-off. In an extreme scenario, investors from both countries might be forced to divest their holdings of equities and debt instruments. 
Meanwhile, S&amp;P Global Ratings on Friday stated that Trump's tariff increases are expected to primarily affect China's coastal provinces, including Guangdong, Jiangsu, Shandong, and Zhejiang, along with Shanghai, a key port and financial hub.
That being said, a possible easing of trade tensions,&nbsp;China last week,<a href="https://www.benzinga.com/news/global/25/04/45004954/china-reportedly-begins-exempting-key-us-imports-from-tariffs-including-pharma-and-aerospace-parts"> reportedly began </a>exempting&nbsp;some U.S. imports from high tariffs, including pharmaceutical imports and aerospace parts. Companies in China have been approached by officials to identify essential U.S. goods that are difficult to replace. Furthermore, the 24-member Politburo, led by President Xi Jinping, committed to stabilizing China's economy and employment, and called for support measures for those impacted by tariffs following a meeting last week.
The ADR of Alibaba Group Holding Ltd (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/BABA#NYSE">BABA</a>) climbed 0.8% to close at $120.28 on Friday, while that of PDD Holdings Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/PDD#NASDAQ">PDD</a>) rose 0.72% to close at $104.01. Meanwhile, the ADR of NetEase, Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/NTES#NASDAQ">NTES</a>) slid 0.05% to close at $105.86, as per <a href="https://www.benzinga.com/pro/" target="_blank" rel="noreferrer noopener">BenzingaPro</a>.
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<li>READ MORE:&nbsp;<a href="https://benzinga.com/news/25/04/45027945/does-anybody-honestly-believe-manufacturing-is-coming-back-to-the-us-one-person-asked-says-youd-have-to-pay-" target="_blank" rel="noreferrer noopener">&#8216;Does Anybody Honestly Believe Manufacturing Is Coming Back To The US?&#8217; One Person Asked. Says, &#8216;You&#8217;d Have To Pay Americans $40–$50/Hr&#8217;</a></li>
</ul>
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Disclaimer:&nbsp;This content was partially produced with the help of AI tools and was reviewed and published by Benzinga editors.

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NTES

Citigourp Global Markets 2% Protected Notes Linked To The Djia

16 Million Jobs At Risk In China As US Tariffs Hammer Manufacturing And Retail Sectors, Goldman Sachs Warns

Pershing Square's Bill Ackman has hailed Amazon.com Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/AMZN#NASDAQ">AMZN</a>) founder Jeff Bezos-backed Slate Auto as the company recently revealed its $20,000 EV truck.
What Happened: Quoting a post that shared a Slate Auto commercial on social media platform X, Ackman hailed the company's modular approach to its vehicle on Saturday.
<figure class="wp-block-embed is-type-rich is-provider-twitter wp-block-embed-twitter"> 
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<blockquote class="twitter-tweet" data-width="500" data-dnt="true">This is a going to be a big success. We all want more simplicity and flexibility in our lives. <a href="https://t.co/t7o7VYfBFM">https://t.co/t7o7VYfBFM</a>
&mdash; Bill Ackman (@BillAckman) <a href="https://twitter.com/BillAckman/status/1916123387669225910?ref_src=twsrc%5Etfw">April 26, 2025</a></blockquote>
<script async src="https://platform.twitter.com/widgets.js" charset="utf-8"></script></div>
</figure>
"This is a going to be a big success. We all want more simplicity and flexibility in our lives," Ackman shared in his post.
Why It Matters: Slate Auto has only one product on offer, which it calls the ‘Blank Slate.' In its base form, it is a two-seater EV pickup truck in grey with a 150-mile range, but customers can personalize the car in whatever way they want, including a 5-seater SUV.
The company says that with the federal EV credit, the <a href="https://www.benzinga.com/tech/25/04/45006513/jeff-bezos-backed-tesla-rival-unveils-20000-modular-ev-pickup-truck-with-customization-at-the-forefront">car could cost $20,000</a>, which is significantly cheaper than the likes of Tesla Inc.'s (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/TSLA#NASDAQ">TSLA</a>) Cybertruck or Rivian Automotive Inc.'s (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/RIVN#NASDAQ">RIVN</a>) R1T.
While Slate Auto says the company aims to begin deliveries by 2026, the EV pickup truck has already garnered a lot of <a href="https://www.benzinga.com/tech/25/04/44784826/jeff-bezos-backed-slate-auto-to-take-on-elon-musks-tesla-rivian-with-budget-ev-pickup-report">buzz on social media</a> platforms like Reddit.&nbsp;
Interestingly, the release comes at a time when the domestic EV market in the U.S. is <a href="https://www.benzinga.com/25/04/44755934/us-q1-ev-sales-data-shows-106-yoy-growth-tesla-experiences-decline-but-still-dominates-domestic-ev-sales">experiencing a surge</a>, which Slate Auto could take advantage of given its product's competitive pricing.
<figure class="wp-block-image size-large"><img loading="lazy" decoding="async" width="1024" height="214" src="https://editorial-assets.benzinga.com/wp-content/uploads/2025/04/28033155/AMZN-1024x214.jpg" alt="" class="wp-image-890272" srcset="https://editorial-assets.benzinga.com/wp-content/uploads/2025/04/28033155/AMZN-1024x214.jpg 1024w,https://editorial-assets.benzinga.com/wp-content/uploads/2025/04/28033155/AMZN-300x63.jpg 300w,https://editorial-assets.benzinga.com/wp-content/uploads/2025/04/28033155/AMZN-768x160.jpg 768w,https://editorial-assets.benzinga.com/wp-content/uploads/2025/04/28033155/AMZN-1536x321.jpg 1536w,https://editorial-assets.benzinga.com/wp-content/uploads/2025/04/28033155/AMZN.jpg 1647w" sizes="(max-width: 1024px) 100vw, 1024px" /></figure>
Amazon scores Well on metrics like Momentum, Growth, and Quality, and has a Satisfactory score in the Value metric. For more such insights, sign up for<a href="https://www.benzinga.com/premium/ideas/benzinga-edge-2#:~:text=Turn%20Market%20Chaos,when%20markets%20rebound"> Benzinga Edge</a> today!
Check out more of Benzinga's Future Of Mobility coverage by<a href="https://www.benzinga.com/topic/mobility"> following this link.</a>
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Image Via Slate Auto

Tech

General

AMZN

RIVN

TSLA

Bill Ackman Hails Jeff Bezos-Backed Tesla Rival Slate Auto, Says It Will Be 'A Big Success'

Huawei Technologies is reportedly preparing to test its most powerful artificial intelligence processor to date, with hopes of <a href="https://www.benzinga.com/25/03/44356270/huawei-develops-in-house-chips-to-counter-us-sanctions-and-leap-ahead-in-the-tech-war">replacing high-end chips</a> from U.S. giant Nvidia Corporation (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/MSFT#NASDAQ">MSFT</a>), even as U.S. sanctions continue to stifle China&#8217;s semiconductor ambitions.
What Happened: Huawei has begun the testing phase of its new AI chip, the Ascend 910D, which is designed to rival Nvidia's flagship processors, <a href="https://www.wsj.com/tech/chinas-huawei-develops-new-ai-chip-seeking-to-match-nvidia-8166f606?mod=tech_lead_pos1">reported</a> the Wall Street Journal on Sunday, citing people familiar with the matter.
The chip will undergo a series of technical tests, with samples expected to be ready by late May. The Ascend 910D aims to surpass Nvidia's H100 chip, a popular choice for AI training tasks.
This move marks a significant step forward for Huawei's semiconductor division, which has faced substantial challenges due to <a href="http://v/">U.S. sanctions over</a> the past six years.
See Also:&nbsp;<a href="https://benzinga.com/25/04/45003790/mark-cuban-slams-amazon-for-ripping-off-american-sellers-as-tariffs-are-predicted-to-boost-ecommerce-brands-profi" target="_blank" rel="noreferrer noopener">Mark Cuban Slams Amazon For ‘Ripping Off American Sellers' As Trump Tariffs Are Predicted To Boost Ecommerce Brands' Profits</a>
This year, Huawei plans to ship over 800,000 Ascend 910B and 910C chips. Customers include state-run telecoms and companies like ByteDance, the report noted, citing the sources. 
However, Huawei has been struggling to manufacture these chips on a large scale due to <a href="https://www.benzinga.com/25/04/44963176/chinese-tech-firms-led-by-alibaba-hoard-nvidia-ai-chips-amid-us-sanctions">obstacles in its supply chain</a>. The company has been excluded from working with Taiwan Semiconductor Manufacturing Co. (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/TSM#NYSE">TSM</a>).
Its closest alternative, Semiconductor Manufacturing International, is also restricted from acquiring the latest chip-making technology.
Why It&#8217;s Important: Earlier this month, the U.S. government placed Nvidia's H20 chip—its most advanced processor available for sale in China without a license—on a list of semiconductors facing sales restrictions.
Nvidia revealed that this move would lead to a<a href="https://www.benzinga.com/25/04/44830406/nvidia-to-take-55-billion-hit-over-china-chip-export-restrictions-but-top-analyst-dan-ives-says-hes-not-overly-concerned-all-part-of-the-high-game-of-poker"> $5.5 billion financial hit</a>.
On Sunday, Chamath Palihapitiya spoke about how <a href="https://www.benzinga.com/25/04/45030669/chamath-palihapitiya-says-nvidia-is-huaweis-new-target-a-national-champion-that-crushed-tech-giants-with-a-low-end-disruptor-strategy">Huawei has effectively executed</a> a &#8220;low-end disruptor&#8221; strategy. This strategy focuses on creating products that match or exceed the quality of industry leaders, but at a more affordable price.
He highlighted several companies Huawei has already surpassed, including Telefonaktiebolaget LM Ericsson (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/ERIC#NASDAQ">ERIC</a>) and Nokia (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/NOK#NYSE">NOK</a>).
Previously, the SPAC king raised concerns that <a href="https://in.benzinga.com/markets/25/04/44891778/nvidia-not-acting-in-us-interests-says-chamath-palihapitiya-questions-how-alibaba-or-deepseek-are-one-step-ahead">Nvidia may not be prioritizing</a> the best interests of the U.S.
Benzinga Edge Stock Rankings places Nvidia&#8217;s growth score in the 94th percentile. Curious how other chip stocks compare? <a href="https://www.benzinga.com/premium/ideas/benzinga-edge-2#:~:text=Turn%20Market%20Chaos,when%20markets%20rebound">Click here to discover more</a>.
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Disclaimer:&nbsp;This content was partially produced with the help of AI tools and was reviewed and published by Benzinga editors.

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MSFT

Nvidia Faces New Challenge As Huawei Tests Powerful Ascend 910D AI Chip Amid US Sanctions, Aiming To Disrupt High-End Market: Report

Global defense budgets reached unprecedented levels in 2024, driven by mounting conflicts and geopolitical strains. A new report from the Stockholm International Peace Research Institute (SIPRI) showcases a sensational increase in military spending across the globe.
What Happened: According <a href="https://www.sipri.org/media/press-release/2025/unprecedented-rise-global-military-expenditure-european-and-middle-east-spending-surges">to</a> SIPRI, military expenditure rose 9.4% to $2.72 trillion. This marks the most drastic annual increase since the Cold War concluded. All regions reported higher defense outlays, with Europe and the Middle East demonstrating particularly speedy growth. 
More than 100 nations enhanced their military budgets, often reallocating funds from other crucial sectors. U.S. military expenditure touched $997 billion, making up 66% of NATO&#8217;s total and 37% of global defense spending.
See Also: <a href="https://www.benzinga.com/news/25/04/44889497/its-offensive-and-just-plain-wrong-trumps-budget-proposal-to-eliminate-head-start-affecting-over-1-million-parents">&#8216;It&#8217;s Offensive And Just Plain Wrong&#8217;—Trump&#8217;s Budget Proposal To Eliminate Head Start, Affecting Over 1 Million Parents</a>
Why It Matters: Europe&#8217;s military expenditure, including Russia, soared 17%, moving past Cold War-era numbers. Russia&#8217;s defense budget alone rose by 38% to an approximate $149 billion, making up 7.1% of its Gross Domestic Product. 
Ukraine, despite major financial difficulties, increased military spending by 2.9% to $64.7 billion, with its defense budget now taking up all available tax revenue.
The report underscores rising concerns about the long-term impact of prioritizing military budgets over social and economic necessities. 
SIPRI warns that the trend could restructure societies for decades to come. In Europe, the ongoing war in Ukraine and ambiguity surrounding U.S. NATO support have prompted increased defense spending.
Read Next: 
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<li><a href="https://www.benzinga.com/markets/25/04/45030778/trump-running-american-economy-like-a-mafia-don-economist-craig-shapiro-draws-parallels-with-russias-president">Trump Running American Economy Like A &#8216;Mafia Don&#8217;: Economist Craig Shapiro Draws Parallels With Russia&#8217;s President</a></li>
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Global

Economics

Global Defense Budgets Surge To $2.7 Trillion As Europe And Middle East Lead Steepest Increase Since Cold War: Report

Buybacks

MIELY

Mitsubishi Electric Launches Share Buyback Program For 60M Shares Worth Up To JPY 100B

In a recent private event,&nbsp;Donald Trump Jr., son of the U.S. President, voiced his support for enhanced business cooperation with Eastern Europe.
What Happened: Trump Jr. underscored his close connections to the region during his address at the Trump Business Vision 2025 event organized by businessman Zoltán Aczél and Portfolio at Budapest, Hungary. He spotlighted his Czechoslovakian roots and language proficiency owing to his mother late Ivana Trump, and applauded the region&#8217;s dramatic evolution over the past five decades, <a href="https://www.portfolio.hu/en/economy/20250425/donald-trump-jr-we-want-to-do-a-lot-of-good-business-with-our-friendly-allies-757309">reported</a> Portfolio.
As the&nbsp;Executive Vice President of the&nbsp;Trump Organization, Trump Jr. praised Hungary&#8217;s robust political leadership, specifically Prime Minister Viktor Orbán. He expressed belief in the potential for successful collaboration between American and Hungarian businesses.
He is hopeful that the U.S.-Eastern Europe ties would generate a lot of business amid threats facing the U.S., Hungary and the Central and Eastern European region.
&#8220;I understand the threat that looms from so many places and it&#8217;s not the evil boogeyman of Russia, but likely China,&#8221; pointed out the U.S. President&#8217;s son. 
Trump Jr. recognized the necessity to diversify the U.S. economy&#8217;s dependencies, pointing out the high concentration of pharmaceutical production in China and advanced chip technology in Taiwan. He proposed that Eastern Europe, with its committed workforce and lower labor costs, could assume many activities currently outsourced to China.
&#8220;Pulling away from China is the first step, the dependence is too high,&#8221; stated Trump Jr.
SEE ALSO:&nbsp;<a href="https://benzinga.com/general/sports/25/04/45027895/why-shaq-wont-share-his-500-million-fortune-with-his-kids-we-aint-rich-im-rich-im-not-going-to-hand-it-to-you-you-gotta-earn-it" target="_blank" rel="noreferrer noopener">Why Shaq Won't Share His $500 Million Fortune With His Kids: ‘We Ain't Rich. I'm Rich. I'm Not Going to Hand It to You, You Gotta Earn It&#8217; &#8211; Benzinga</a>
Why It Matters: This comes at a time when the U.S. is experiencing strained relations with China. The ongoing trade war with China has led to a significant decrease in U.S. imports <a href="https://www.benzinga.com/25/04/45026616/trumps-trade-war-causes-sharp-decline-in-us-imports-from-china">from the</a> Asian nation, while China&#8217;s Ministry of Commerce has <a href="https://www.benzinga.com/markets/25/04/44973283/china-denies-trumps-trade-talk-assertion-calls-for-abolition-of-unilateral-tariffs-no-factual-basis">denied rumors</a> of ongoing trade discussions with the U.S.
Against this backdrop, analysts suggest there are concerns that China <a href="https://www.benzinga.com/news/global/25/04/44892820/xi-jinping-could-woo-europe-with-a-potential-china-deal-to-undercut-trumps-tariff-strategy-expert-warns">might leverage</a> the strained U.S.-EU relations to its benefit, leading Beijing to shift the majority exports to Europe.
Trump Jr.&#8217;s call for increased cooperation with Eastern Europe could be seen as a strategic move to diversify the U.S.&#8217;s economic dependencies amid these ongoing tensions. Despite not being a member of the Trump administration, Trump Jr. was hopeful about the renewal of the expired double tax treaty between the U.S. and Hungary, citing the strong relationship between his father, Donald Trump and Prime Minister Orbán.
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Image via Shutterstock
Disclaimer:&nbsp;This content was partially produced with the help of AI tools and was reviewed and published by Benzinga editors.

Trump Jr. Leans On His Czech Roots To Boost US-Eastern Europe Ties While 'Pulling Away' From China: 'It's Not The Evil Boogeyman Of Russia, But Likely China'

Consolidated Financial Results Revenue: 5,521.7 billion yen (5% increase year-on-year) Operating profit: 391.8 billion yen (19% increase year-on-year) Profit before income taxes: 437.2 billion yen (20% increase year-on-year) Net profit attributable to Mitsubishi Electric Corp. stockholders: 324.0 billion yen (14% increase year-on-year)

Earnings

Mitsubishi Electric's FY25 Revenue ¥5.521T, Up 5% YoY; Net Profit Attributable To Stockholders ¥324B, Up 14% YoY

CRWD

CrowdStrike Redefines Cybersecurity With Autonomous Charlotte AI Agentic Platform

SYNA

Synaptics Expands Veros Lineup With First Wi-Fi 7 SoCs Tailored For High-Performance, Low-Power IoT Applications

Roper Technologies, Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/ROP#NASDAQ">ROP</a>) will release earnings results for the first quarter, before the <a href="https://www.benzinga.com/quote/ROP/earnings">opening bell on Monday, April 28.</a>
Analysts expect the Sarasota, Florida-based company to report quarterly earnings at $4.74 per share, up from $4.41 per share in the year-ago period. Roper Technologies projects to report quarterly revenue at $1.88 billion, compared to $1.68 billion a year earlier, according to data from <a href="https://pro.benzinga.com/dashboard">Benzinga Pro</a>.
On March 24, Roper Technologies disclosed a deal to acquire CentralReach from Insight Partners for a net purchase price of around $1.65 billion.
Roper Technologies shares fell 0.4% to close at $557.70 on Friday.
Benzinga readers can access the latest analyst ratings on the <a href="https://www.benzinga.com/analyst-ratings/analyst-color/22/09/28888638/exclusive-study-finds-benzinga-analyst-ratings-data-yields-market-beating-strategie">Analyst Stock Ratings</a> page. Readers can sort by stock ticker, company name, analyst firm, rating change or other variables.
Let's have a look at how Benzinga's most-accurate <a href="https://www.benzinga.com/quote/rop/analyst-ratings">analysts have rated the company</a> in the recent period.
<ul>
<li>JP Morgan analyst Stephen Tusa maintained a Neutral rating and cut the price target from $558 to $465 on April 8, 2025. This analyst has an accuracy rate of 66%.</li>
<li>Stifel analyst Brad Reback initiated coverage on the stock with a Buy rating and a price target of $685 on March 27, 2025. This analyst has an accuracy rate of 71%.</li>
<li>Oppenheimer analyst Christopher Glynn maintained an Outperform rating and raised the price target from $630 to $640 on Jan. 31, 2025. This analyst has an accuracy rate of 77%.</li>
<li>Raymond James analyst Brian Gesuale reiterated a Strong Buy rating and increased the price target from $620 to $655 on Jan. 31, 2025. This analyst has an accuracy rate of 74%.</li>
<li>Barclays analyst Julian Mitchell maintained an Underweight rating and cut the price target from $569 to $562 on Jan. 8, 2025. This analyst has an accuracy rate of 72%.</li>
</ul>
Considering buying ROP stock? Here&#8217;s what analysts think: 
<figure class="wp-block-image size-large is-resized"><img loading="lazy" decoding="async" width="1024" height="587" src="https://editorial-assets.benzinga.com/wp-content/uploads/2025/04/28031822/image-183-1024x587.png" alt="" class="wp-image-890254" style="width:551px;height:auto" srcset="https://editorial-assets.benzinga.com/wp-content/uploads/2025/04/28031822/image-183-1024x587.png 1024w,https://editorial-assets.benzinga.com/wp-content/uploads/2025/04/28031822/image-183-300x172.png 300w,https://editorial-assets.benzinga.com/wp-content/uploads/2025/04/28031822/image-183-768x440.png 768w,https://editorial-assets.benzinga.com/wp-content/uploads/2025/04/28031822/image-183.png 1122w" sizes="(max-width: 1024px) 100vw, 1024px" /></figure>
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<li><a href="https://www.benzinga.com/analyst-ratings/price-target/25/04/45007044/wall-streets-most-accurate-analysts-give-their-take-on-3-real-estate-stocks-delivering-high-dividend-yields-5">Wall Street&#8217;s Most Accurate Analysts Give Their Take On 3 Real Estate Stocks Delivering High-Dividend Yields</a> </li>
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Photo via Shutterstock

Price Target

Pre-Market Outlook

Analyst Ratings

Trading Ideas

Roper Technologies Gears Up For Q1 Print; Here Are The Recent Forecast Changes From Wall Street's Most Accurate Analysts

<ul>
<li>TARA-002 demonstrates 100% complete response rate at any time and 67% 12-month landmark complete response rate in BCG-Unresponsive patients</li>
<li>TARA-002 demonstrates 76% complete response rate at any time and 43% 12-month landmark complete response rate in BCG-Naïve patients</li>
<li>Favorable safety and tolerability profile with no Grade 3 or greater treatment-related adverse events</li>
<li>On track to present updated interim data from approximately 25 six-month evaluable BCG-Unresponsive patients by the end of 2025</li>
<li>Company to host conference call and webcast on Monday, April 28, 2025, at 8:30 a.m. ET</li>
</ul>

TARA

Reported Saturday, Protara Therapeutics Shares Interim Results Highlighting Durable Clinical Responses With TARA-002 In High-Risk NMIBC

The authorities initially prioritized vaccination of adults aged 65 and over, especially those with comorbidities. On April 25, the French health authorities decided to suspend the use of IXCHIQ&#xAE; in persons aged 65 years and older pending further investigation. This is a response to an ongoing investigation of three cases of SAEs resulting in hospitalization, including one death, after vaccination with IXCHIQ&#xAE; among people in La Reunion. The three individuals who were hospitalized were over 80 years old and had pre-existing comorbidities3. These SAEs were reported through the pharmacovigilance system set up by the French health authorities, and causality has not been definitively established. The HAS maintains its current recommendation for IXCHIQ&#xAE; for people aged 18 to 64 years old as part of the ongoing vaccination campaign.

VALN

Reported Saturday, Valneva Provides Update On IXCHIQ Chikungunya Vaccine Use Following HAS Recommendation And Safety Investigation

<ul>
<li>Pivotal Phase 3 CREST trial results show a 32% reduction in the risk of disease-related events, including high-grade disease recurrence or progression, with sasanlimab in combination with standard of care (SOC) Bacillus Calmette-Guérin (BCG) regimen compared to SOC alone</li>
<li>Sasanlimab, a subcutaneously administered PD-1 inhibitor, in combination with BCG represents the first potential treatment advancement for BCG-naïve, high-risk non-muscle invasive bladder cancer in more than 30 years</li>
<li>Results have been shared with global health authorities to support potential regulatory filings</li>
</ul>

Reported Saturday, Pfizer's Sasanlimab Combination Therapy Shows Strong Event-Free Survival Gains In High-Risk Non-Muscle Invasive Bladder Cancer

First results from SunRISe-1 (Cohort 4) show strong disease-free survival rates across high-grade papillary tumors, demonstrating the potential for bladder preservation with 94 percent of patients avoiding radical cystectomy
95 percent progression-free survival rate at 9-months signals the promise of TAR-200 in this high-risk patient population

Reported Saturday, Johnson & Johnson's TAR-200 Monotherapy Demonstrates Strong Early Efficacy In BCG-Unresponsive Bladder Cancer, Achieving Over 80% Disease-Free Survival

<ul>
<li>Robust 24-month complete response rate of 42.3% by K-M for cretostimogene monotherapy in BOND-003 Cohort C</li>
<li>58.3% of patients showed durable complete responses by K-M at 24 months</li>
<li>97.3% of all treated patients remained free from progression to MIBC at 24 month</li>
<li>91.6% of responders remained cystectomy-free at 24 month</li>
<li>No Grade 3 or greater treatment-related adverse events or deaths reported</li>
<li>Strong initial Cohort P data reported 90.5% high-grade recurrence-free survival at 3 and 9 months by K-M</li>
<li>Company will host a conference call and webcast at 8 a.m. EDT on Monday, April 28, 2025</li>
</ul>

CGON

Reported Saturday, CG Oncology Reports Durability In BOND-003 Cohort C And Encouraging Early Results In Cohort P For Cretostimogene Grenadenorepvec

A man has become the first non-verbal, as well as only the third person ever, to receive a Neuralink Brain-Chip Interface (BCI) implant.
What Happened: Author Bradford G Smith suffers from ALS or Amyotrophic Lateral Sclerosis, a very rare nervous system disease that severely impacts motor functions. Smith released a video on the social media platform X to share the update on Sunday.
<figure class="wp-block-embed is-type-rich is-provider-twitter wp-block-embed-twitter"> 
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<blockquote class="twitter-tweet" data-width="500" data-dnt="true">I am the 3rd person in the world to receive the <a href="https://twitter.com/neuralink?ref_src=twsrc%5Etfw">@Neuralink</a> brain implant. 1st with ALS. 1st Nonverbal. I am typing this with my brain. It is my primary communication. Ask me anything! I will answer at least all verified users! Thank you <a href="https://twitter.com/elonmusk?ref_src=twsrc%5Etfw">@elonmusk</a>! <a href="https://t.co/bxYO3SBfA2">pic.twitter.com/bxYO3SBfA2</a>
&mdash; Bradford G Smith (Brad) (@ALScyborg) <a href="https://twitter.com/ALScyborg/status/1916630186382291242?ref_src=twsrc%5Etfw">April 27, 2025</a></blockquote>
<script async src="https://platform.twitter.com/widgets.js" charset="utf-8"></script></div>
</figure>
Smith says that he uses the Neuralink implant to control the cursor on his laptop as well as Grok AI to create a clone of his own voice to speak. The video Smith shared was also edited by the BCI chip.
Why It Matters: The news comes as Elon Musk has touted his Neuralink BCI as technology that will help completely <a href="https://www.benzinga.com/general/biotech/25/04/44892867/elon-musk-says-neuralink-will-help-blind-people-see-again-will-exceed-the-best-human-eyes">blind people see again</a>, the billionaire shared.&nbsp;&nbsp;
Musk also reiterated that robots would <a href="https://www.benzinga.com/25/04/45031447/elon-musk-says-the-best-human-surgeons-have-just-five-years-before-robots-overtake-them-reveals-instance-when-neuralink-had-to-use-a-robot-for-task-impossible-for-a-human">outperform human surgeons</a> in almost 5 years. He said Neuralink "had to use a robot for the brain-computer electrode insertion, as it was impossible for a human to achieve the required speed and precision."
Elsewhere, Neuralink is also eyeing an<a href="https://www.benzinga.com/general/biotech/25/04/44972585/elon-musks-neuralink-eyes-8-5-billion-pre-money-valuation-in-latest-funding-round-report"> $8.5 billion pre-money valuation</a> in its latest round of funding as the company aims to raise over $500 million, in ongoing talks with investors.
Check out more of Benzinga's Future Of Mobility coverage by<a href="https://www.benzinga.com/topic/mobility"> following this link.</a>
Read Next:
<ul>
<li><a href="https://www.benzinga.com/news/25/03/44358022/paralyzed-man-moves-objects-with-his-mind-thanks-to-elon-musks-brain-chip">Paralyzed Man Moves Objects With His Mind—Thanks To Elon Musk&#8217;s Brain Chip</a></li>
</ul>
Image Via Shutterstock

Biotech

Man Battling ALS Becomes First Non-Verbal Patient To Receive Elon Musk's Neuralink Brain Implant

As AI chatbots like OpenAI's ChatGPT, Anthropic's Claude, and Perplexity reshape how users search for information, brands are adjusting their strategies to maintain visibility in this new search environment, which is increasingly displacing traditional search engines like Alphabet Inc.'s (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/GOOG#NASDAQ">GOOG</a>) (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/GOOGL#NASDAQ">GOOGL</a>) Google.
What Happened: In a shift that threatens Google's dominance, brands are adopting new strategies to ensure they remain visible in the results generated by AI chatbots, <a href="https://www.ft.com/content/9cc6cc0b-759f-4b8e-9ed1-9e32ad0fe22f">reported</a> the Financial Times on Sunday.
Instead of clicking through to websites, many users now rely on AI's synthesized responses, which have decreased web traffic by up to 25%, the report noted, citing research from consultancy Bain.
Taking cognizance of this development, companies like Brandtech and Profound have developed tools that monitor how often brands appear in AI-driven responses, providing insights on how businesses can optimize for these models.
See Also: <a href="https://www.benzinga.com/25/04/44982688/alphabet-q1-earnings-preview-google-parent-stock-at-fork-in-the-road-while-antitrust-concerns-remain" target="_blank" rel="noreferrer noopener">Alphabet Q1 Earnings Preview: Google Parent Stock At ‘Fork In The Road,' While Antitrust Concerns Remain</a>
"This is about much more than just getting your website indexed in their results. This is about recognizing large language models as the ultimate influencer," said Jack Smyth, partner at Brandtech.
Brandtech has developed a &#8220;Share of Model&#8221; tool that helps brands analyze their visibility in AI search results and provides recommendations for optimizing website text and images.&nbsp;
Profound, which secured $3.5 million in seed funding in August, led by Khosla Ventures, offers a data analytics platform that enables brands to monitor popular industry queries and assess their standing within AI search results, the report said.
Why It's Important: On Thursday, Alphabet <a href="https://www.benzinga.com/25/04/44995955/alphabet-q1-earnings-highlights-google-search-youtube-cloud-show-robust-momentum">posted first-quarter revenue</a> of $90.23 billion, a 12% rise compared to the same period last year, beating Wall Street's expectation of $89.2 billion. Revenue from Google Search reached $50.7 billion, up from $46.2 billion a year earlier.
&nbsp;The strong performance helped ease investor concerns about rising competition from AI chatbots like Elon Musk's Grok and fears that Google's own Gemini chatbot and AI-generated summaries might be cutting into its traditional ad-driven search traffic, the report said.
Deepwater Asset Management's Gene Munster previously said that Google's existing search format, which blends AI overviews, blue links, and organic results, <a href="https://www.benzinga.com/25/04/44999838/can-google-adapt-like-amazon-or-will-it-face-ebays-fate-gene-munsters-candid-take-on-the-search-giants-path-forward-in-the-age-of-ai">may fall short against newer</a>, more streamlined search experiences offered by models like Grok, ChatGPT, and Claude.
Price Action: In after-hours trading, Alphabet Inc.&#8217;s Class A shares slipped 0.16% to $161.70, while Class C shares dipped 0.1% to $163.68, according to <a href="https://pro.benzinga.com/dashboard">Benzinga Pro data</a>.
Alphabet holds a growth score of 64.44%, based on Benzinga Edge Stock Rankings. <a href="https://www.benzinga.com/premium/ideas/benzinga-edge-2#:~:text=Turn%20Market%20Chaos,when%20markets%20rebound">Click here to see how it compares to other companies</a> in the sector.
Photo Courtesy: Ascannio On Shutterstock.com
Read Next:
<ul>
<li><a href="https://www.benzinga.com/25/04/44986406/if-you-invested-1000-in-google-stock-when-it-acquired-youtube-heres-how-much-youd-have-today" target="_blank" rel="noreferrer noopener">If You Invested $1,000 in Google Stock When It Acquired YouTube, Here's How Much You'd Have Today</a></li>
</ul>
Disclaimer:&nbsp;This content was partially produced with the help of AI tools and was reviewed and published by Benzinga editors.

GOOG

GOOGL

Google Faces Growing Threat As Chatbots Reshape How Users Search For Brands: Are ChatGPT, Claude And Others AI Bots Set To Be The 'Ultimate' Influencers?

Chinese manufacturers are suspending operations and pursuing alternative markets as U.S. tariff increases take effect, creating ripple effects across global supply chains and threatening millions of jobs.
What Happened: Chinese factories are pausing production due to the impact of U.S. tariffs, as <a href="https://www.cnbc.com/2025/04/28/chinese-factories-stop-production-eye-new-markets-as-us-tariffs-hit.html?ref=biztoc.com">reported</a> by CNBC on Monday. The lost orders are affecting jobs and prompting Chinese exporters to explore new sales strategies, such as livestreaming at home.
According to Cameron Johnson, a senior partner at consulting firm Tidalwave Solutions, factories producing toys, sporting goods, and low-cost Dollar Store-type goods are currently the most affected. &#8220;While not large-scale yet, it is happening in the key [export] hubs of Yiwu and Dongguan, and there is concern that it will grow,&#8221; Johnson said. The impact of recent tariff hikes exceeding 100% is &#8220;way bigger&#8221; than the COVID-19 pandemic&#8217;s disruption, says Ash Monga, CEO of Imex Sourcing Services. 
Woodswool, an athleticwear manufacturer near Shanghai, reports all U.S. orders have been canceled, with over half its production once destined for American customers. The company has pivoted to domestic sales through Baidu&#8216;s (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/BIDU#NASDAQ">BIDU</a>) livestreaming platform, though its new sales channel generates only modest revenue.
See Also: <a href="https://www.benzinga.com/25/04/44999959/how-the-us-china-trade-war-is-unintentionally-boosting-demand-for-intels-older-chips-amid-economic-uncertainty">Intel&#8217;s Older Parts Are In Demand Thanks To US-China Trade War: &#8216;Tariffs Have Everybody Hedging Their Bets,&#8217; Says Executive</a>
Why It Matters: Many companies are diversifying production to India over Southeast Asia, while others are turning from U.S. customers to those in Europe and Latin America. Some companies have already built businesses on other trade routes from China.
For U.S. investors, these developments signal potential disruption in supply chains and pricing. Goldman Sachs has downgraded China&#8217;s Gross Domestic Product growth <a href="https://www.benzinga.com/government/regulations/25/04/44740040/chinas-growth-outlook-dims-as-trumps-125-tariffs-put-millions-of-jobs-at-risk-goldman-warns?utm_source=chatgpt.com">forecasts to 4.0% for 2025 and 3.5% for 2026</a>, below the government&#8217;s 5% target.
The U.S.-China trade war, under President Donald Trump&#8216;s administration, has led to a <a href="https://www.benzinga.com/25/04/45026616/trumps-trade-war-causes-sharp-decline-in-us-imports-from-china">significant decrease in U.S. imports </a>from China. In response, China has started to<a href="https://www.benzinga.com/news/global/25/04/45004954/china-reportedly-begins-exempting-key-us-imports-from-tariffs-including-pharma-and-aerospace-parts"> exempt some U.S. imports</a> from high tariffs, indicating a possible easing of trade tensions.
The iShares China Large-Cap ETF (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/FXI#NYSE">FXI</a>), a widely followed U.S.-listed fund that tracks major Chinese companies, has fallen 4.38% since Trump introduced a 34% &#8220;reciprocal&#8221; tariff on Chinese imports.
Read Next: 
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<li><a href="https://www.benzinga.com/markets/25/04/45005825/us-has-tons-of-solutions-to-secure-rare-earth-production-if-china-halts-exports-experts-say-but-warn-of-significant-challenges">US Has &#8216;Tons Of Solutions&#8217; To Secure Rare Earth Production If China Halts Exports, Experts Say, But Warn Of Significant Challenges</a></li>
</ul>
Disclaimer: This content was partially produced with the help of AI tools and was reviewed and published by Benzinga editors.
Image Via Shutterstock

BIDU

Trump Tariffs Prompt Suspension Of Chinese Factory Operations And Shift To New Markets

<ul>
<li>Largest multi-center prospective Investigational Device Exemption (IDE) study for multi-port robotic-assisted urologic surgery in the U.S. presented as&nbsp;a late-breaker at the American Urologic Association annual meeting Company confirms Hugo RAS system submission to&nbsp;the U.S. Food and Drug Administration</li>
</ul>

Reported Saturday, Medtronic's Hugo RAS System Achieves 98.5% Surgical Success Rate In Largest U.S. Robotic-Assisted Urology Study

<ul>
<li>One-year clinical trial data for the next-generation, investigational, Sphere-360&#x2122; single-shot PFA catheter show impressive safety, performance, and efficiency results for paroxysmal Afib</li>
<li>Dual-energy (RF/PF), focal Sphere-9&#x2122; catheter demonstrates efficacy for linear ablation in persistent AFib</li>
<li>Medtronic continues legacy of leadership in innovation, showcasing arrhythmia management portfolio at Heart Rhythm Society annual meeting</li>
</ul>

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